LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan, Vice President of LC Resources and world renowned expert on HPLC, is able to highlight common problems and provide remedies for them.

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Column Watch keeps readers up-to-date with new column technology trends in all branches of chromatography and reviews developments in existing technology lines. Columnist Ron Majors, Chromatography Business Development Manager for Agilent Technologies and established authority on new column technologies also compiles the annual Pittcon round-up for LCGC North America.

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GC Connections provides advice for regular users of gas chromatography, John Hinshaw is the editor of 'GC Connections' and has been a columnist with LCGC for over 27 years, covering separation fundamentals, column care, instrument troubleshooting and many other topics. John is one of the premier experts on gas chromatography active in the industry today. He is currently a senior scientist with BPL Global, Portland, Oregon and is a member of LCGC?s editorial advisory board.

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Sample Preparation Perspectives' editor Ron Majors examines technologies and methodologies for getting your samples ready for chromatographic analysis.

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Coupling Matters introduces novel hyphenations in sample preparation, separation and detection systems. This column, edited by Robert Shellie from the Australian Centre for Research on Separation Science (ACROSS) at the University of Tasmania, provides a must-read for anyone interested in working with coupled systems.

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CE Currents provides practical advice on maximizing the use of capillary electrophoresis and related techniques. Kevin Altria, Senior Principal Scientist at GlaxoSmithKline and leading CE exponent, demonstrates how to develop robust CE methods, how to troubleshoot existing ones and describes new innovations in instrumentation and equipment.

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Kate Yu is the new editor of 'MS-The Practical Art' and will bring her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC starting in 2012. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers.

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Questions of Quality offers guidance on quality issues relevant to all separation scientists. Method development, data handling, chromatography data systems and laboratory information management systems are covered by leading industry consultant Robert McDowall.

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Practical Data Handling tackles the subject of chemometrics. Yvan Vander Heyden from Vrije Universiteit Brussels, Belgium, a driving force behind the application of chemometrics in analytical chemistry, describes how the use of such chemometric techniques allows chromatographers to improve both the design of robust analytical methods and the subsequent interpretation of derived results.

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Michael Swartz reviews all that is new in the world of HPLC and UHPLC instrumentation and discusses the practical questions involved in their application to a variety of analyses.

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Ira Krull, editor of 'Biotechnology Today', is an associate professor of chemistry at Northeastern University, Boston, Massachusetts, USA, and a member of LCGC's editorial advisory board. Co-editor Anurag Rathore is a consultant and associate professor with the Indian Institute of Delhi, India.

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With each installment of this column, a different industry veteran covers an aspect of the evolution and continued development of the science of chromatography, from its birth to its eventual growth into the high-powered industry we see today.

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A sometimes controversial viewpoint on developments, trends and factors affecting those working within the separation science industry.

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Ira Krull and Michael Swartz are co-editors of 'Validation Viewpoint'.

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Tim Wehr, editor of "Directions in Discovery," is LCGC's resident expert on the topic of drug discovery, and is currently a staff scientist with Bio-Rad Laboratories, Hercules, California.

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Leslie S. Ettre, editor of "Milestones in Chromatography," has been part of the chromatography industry for over 50 years, and is one of the most respected figures in the field. He was with perkinElmer Corp., Shelton, Connecticut, for over 30 years, and is currently a member of LCGC's editorial advisory board.

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