A new procedure is proposed that provides identity parameters for headspace-applicable residual solvent Class 1 and Class 2 compounds addressed in the current US Pharmacopeia <467> method.
The second part of the series covering the fundamentals of instrumentation for headspace sampling discusses vial thermostating, pressurization and transfer to the gas chromatograph's inlet.
Supercritical fluid chromatography (SFC) is a quasi-gas phase technique used to separate a variety of compounds in natural products, fragrances, fine chemicals and pharmaceutical applications.