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LCGC TV: New Carbon-Based Phases for 2D LC: In this new video clip from LCGC TV, Dwight Stoll of Gustavus Adolphus College discusses the development of new carbon-based phases for 2D LC that are well characterized and understood.

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LCGC COLUMNISTS 2014

Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase


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Features
Combining Orthogonal Comprehensive Two-Dimensional Liquid Chromatography Methods in Food Analysis
This review illustrates the benefits of LCXLC in food analysis and discusses the combination of LC modes used in the two dimensions, and the nature of the samples analyzed.
Finding a Needle in a Haystack
Here, we examine the various way that chromatographers and chromatography data-handling systems locate and measure peaks.
HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies
The latest approaches to antibody characterization go beyond ion-exchange, size-exclusion, and reversed-phase modes to make use of affinity, hydrophobic interaction, mixed-mode, and HILIC techniques.
How to Get More Out of Modern HPLC Systems
Richard Henry discusses what chromatographers need to learn, from measuring dispersion and using Van Deemter and Van 't Hoff plots to getting familiar with mobile phase variables.
When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration
The top five adulterated foods, the latest contaminants found in them, and the methods to detect those compounds
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