Despite the utility of high performance liquid chromatography (HPLC) simulators, we found that all the free and low-cost simulators were outdated or had extremely limited functionality, so we created one that addressed these shortcomings.
Limonin was separated from other components in citrus juice sample matrices by reversed-phase chromatography with ultraviolet detection.
The regulatory and practical issues that surround allergenic fragrance use within cosmetics and cleaning products are explored in this article.
The use of a mass spectrometer in quantitative analysis exploits its exquisite selectivity and sensitivity as a detector, allowing a signal to be ascribed to a particular chemical entity with high certainty, even when present in a sample at a low concentration. There are, however, some special considerations that are necessary when a mass spectrometer is used as a quantitative tool.
By LCGC Editors
We recently spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem mass spectrometry (LC–MS-MS) in their research.
In most countries, herbal medicinal products (HMPs) are introduced into the market without proper scientific evaluation or enforced safety and toxicological studies.
When pyrolyzed, macromolecules will decompose into smaller fragments that can have the appropriate volatility for gas chromatography (GC) separation and analysis.
In this installment of "Sample Prep Perspectives," we cover some of the basic scientific principles behind solid-phase extraction (SPE) to allow the correct mode of extraction to be selected through an understanding of how analytes interact with and are separated by the sorbent.
By Tony Taylor
There are many aspects of analytical science which abound with myth and legend – but gas chromatography – mass spectrometry (GC-MS), and more specifically the electron ionization (EI) process, stands out as the technique which has given rise to the largest number of ‘urban myths’ and misunderstandings.
In this blog installment, I would like to share a little advice with those of you who are attending your first major conference.
The Chromatography Forum of the Delaware Valley is currently seeking nominations for the 2017 Dal Nogare Award.
The University of Leicester and Glenfield Hospital in Leicester, UK, are starting a clinical trial into a gas chromatography–field asymmetric ion mobility spectrometry sensor (Owlstone Nanotech Ltd.) for the detection of early-stage lung cancer.
Thermo Fisher Scientific (Waltham, Massachusetts, USA) has acquired Advanced Scientifics, Inc. (ASI) (Millersburg, Pennsylvania, USA) for $300 million (US) in cash.
Vinyl flooring in the home could be a key source of phthalates ingested and inhaled by children, according to a new study. The work was performed as part of an ongoing project by the Columbia Center for Children’s Environmental Health (CCCEH) at Columbia University in New York, USA, and followed a cohort of women and children living in New York city to investigate the impact of phthalate exposure on the health of children.
Joseph Jack Kirkland, considered by many to be one of fathers of high performance liquid chromatography (HPLC), is the winner of LCGC’s 2015 Lifetime Achievement Award.
Tuesday, March 31, 2015 — 8:00 am PDT/ 11:00 am EDT/ 4:00 pm GMT/ 5:00 pm CEST
Thursday, April 2, 2015 — 8:00 am PDT/ 11:00 am EDT/ 4:00 pm BST/ 5:00 pm CEST
Tuesday, April 7, 2015 — 8:00 am PDT / 11:00 am EDT / 4:00 pm BST / 5:00 pm CEST
Featured: Applications of Ion Chromatography
You know the classic uses of ion chromatography (IC), like measuring inorganic ions in drinking water. But do you know what else it can do?
HPLC troubleshooting guide to cycling baselines and pressure fluctuations from LCGC's ChromAcademy.
Instrument manufacturers try to convince us that mass spec is just another detector. Most of us who work with LC-MS know that’s simply not the case – they can be maintenance intensive, unforgiving and generate complex information. When they’re not working it can be difficult to work out exactly where the problem lies. Here’s some advice to point you in the right direction
A question about column dead volume. If the hold-up volume (time) is the extra-column dead volume expressed in time or volume. What is the column dead volume and how can it be calculated?
CHROMacademy delivers key knowledge quickly in bite-size modules, and to prove this here is our seven point guide to understanding atmospheric pressure chemical ionization.
It is of particular importance to reduce extra column volumes when using small volume columns or UHPLC. However, where do these extra column volumes come from, how can they be minimized, and what effect do they have on chromatography?