Incognito goes back to basics with standard labora...
Dr Kevin Cooper of the Institute for Global Food S...
By LCGC Editors
LCGC recently spoke with the 2014 LCGC Emerging Leader in Chromatography award winner, Andre de Villiers, an Associate Professor of Science at Stellenbosch University in South Africa, about his current research analyzing natural products, his various interests and collaborations in analytical chemistry, and his role as a teacher.
Noteworthy new HPLC systems and related products
A review of LC methods and strategies for the chromatographic separation of short RNA oligonucleotides
By LCGC Editors
How to spot weaknesses in methods before problems occur
How does a GC system set and control gas pressures, flows, and carrier gas velocities electronically?
This article describes the development of a new data-independent acquisition (DIA) workflow for protein quantification that uses a mass spectrometer that combines three types of mass analyzers to achieve lower limits of detection (LOD), higher sensitivity, more accurate quantitative results, wider dynamic range, and better reproducibility than existing high-resolution accurate-mass (HRAM) tandem mass spectrometry (MS-MS) DIA workflows.
In most countries, herbal medicinal products (HMPs) are introduced into the market without proper scientific evaluation or enforced safety and toxicological studies.
Worldwide trends in illicit drug use and production have shifted toward an increase in synthetic analogues and the emergence of new variations in their manufacture.
Green analytical chemistry is a widely recognized concept that has led to the development of new analytical methods with reduced environmental impact and minimized analyst occupational exposure. This article presents the most recent progress in the development of greener sample preparation and chromatographic separation techniques.
In sample preparation, what does "high-throughput" really mean?
This article discusses the benef ts of using automated dispersive solid-phase extraction (dSPE) rather than standard SPE in urine analysis.
A program was formulated to help educate public opinion leaders on the fundamentals of unconventional natural gas and oil extraction, to convey the current state of research on the topic, and to disseminate and discuss prospective regulations that have been formulated over the past two to three years.
By Tony Taylor
Much has been written about options for increasing efficiency in HPLC ? primarily through the use of core shell and sub 2 ?m particles, which have been used to increase efficiency, speed up separations or increase peak capacity. However, many separations can only be effectively improved, by optimising selectivity ? resolution is a function of selectivity, efficiency and retention, with selectivity being the most effective at achieving good resolution.
Scientists at the Norwegian Defence Research Establishment (Kjeller, Norway) are working in collaboration with the University of Oslo (Oslo, Norway) to develop new methods to detect the illicit use of nerve agents. In a recent study published in the journal Analytical Chemistry, the team presented a novel method for the quantification of nerve agent metabolites in human serum and urine by combining salting-out assisted liquid–liquid extraction (SALLE) and on-line solid-phase extraction–liquid chromatography–tandem mass spectrometry (SPE–LC–MS–MS).
LCGC Magazine is pleased to announce the addition of Douglas E. Raynie to its editorial advisory board.
Pittcon 2015 has announced the recipients of 14 prestigious awards honoring scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy.
Researchers from CSIRO Oceans and Atmosphere Flagship in Hobart, Australia, have published a new approach to monitoring plastic exposure in live birds. Featured in the journal Methods in Ecology and Evolution, the study describes the sampling of preen oil collected from seabirds using a simple swabbing method for gas chromatography coupled to mass spectrometry (GC–MS) analysis.1
In a new study published in the journal Electrophoresis, a metabolomics approach based on ultrafiltration followed by capillary electrophoresis coupled with mass spectrometry (CE–ESI–MS) is presented for the fingerprinting of polar metabolites in blood serum.
In this new e-book, leading experts present the latest analytical tools for characterizing biopharmaceuticals, including chromatographic methods, mass spectrometry methods, and focused methods for analyzing carbohydrates on therapeutic glycoproteins.