Where Separation Science is Heading: Quotes

Celebrating 25 Years of LCGC Cover
Quotes from leading separation scientists on the future of separation science and the challenges that must be addressed.


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Featured LCGC Interviews

The Benefits of AQbD

The benefits of an analytical quality by design (AQbD) approach to method development cannot be underestimated. The Column spoke to Changqin Hu and Xia Zhang from the National Institutes for Food Drug Control, in Beijing, China, about their work developing a dual-gradient elution stability-indicating method for cloxacillin within an AQbD framework.

Rapid Trace Analysis of Multiresidue Contaminants

Mira Petrovic from the Catalan Institute for Water Research (ICRA) in Girona, Spain, reveals the advantages and practical applications of a novel method she developed for the multiresidue trace analysis of pharmaceutical compounds and their corresponding metabolites and transformation products using dual-column liquid chromatography (LC) coupled to tandem mass spectrometry (MS/MS).

Gas Chromatography

The LCGC Blog: Potential for Use of Stable Isotope–Labelled Internal Standards in Gas Chromatography–Vacuum Ultraviolet Spectroscopy Methods

By Kevin A. Schug

Evaluating the ability of gas chromatography–vacuum ultraviolet detection (GC–VUV) to distinguish and correctly identify various isomer and isotopologue forms of an analyte through the lens of spectral similarity.

Sampling Volatiles From Fragranced Consumer Products Using High-Capacity Sorptive Extraction

By Lara Kelly, David Barden

This study describes the analysis of fragranced washing detergent and washing powder using probe-based headspace and immersive sorptive extraction, in conjunction with analysis by thermal desorption–gas chromatography–mass spectrometry (TD–GC–MS). As well as discussing the differences between the two samples, the analyte ranges covered by headspace and immersive sampling are compared.

Mass Spectrometry

Recent Advances in Comprehensive Chromatographic Analysis of Emerging Drugs

By Ira S. Lurie, Lauriane Tremeau-Cayel, Walter F. Rowe

To address the challenges of analyzing new illicit drugs, emerging techniques such as UHPSFC with MS and UV detection, and GC with VUV detection, may be needed, particularly for distinguishing positional isomers and diastereomers.

LCGC Announces the 2018 Winners of the Lifetime Achievement and Emerging Leader in Chromatography Awards

By LCGC Editors

LCGC, the leading resource for separation scientists, is proud to announce that Ronald E. Majors and Zachary S. Breitbach are the winners of the 11th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively. Majors and Breitbach will be honored in a symposium as part of the technical program at the Pittcon 2018 conference in Orlando, Florida, on February 26, 2018.

Sample Preparation

Analysis and Fate of Surfactants in the Aquatic Environment

By LCGC Editors

According to Analysis and Fate of Surfactants in the Aquatic Environment (Volume 40 of Wilson & Wilson's Comprehensive Analytical Chemistry), an understanding of the fate and behaviour of organic chemicals, such as surfactants?

Partner Organizations

Sepu, China's Largest Chromatography Training Site

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Chinese American Chromatography Association (CACA)

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The LCGC Blog: Three Peaks Shapes You Really Don’t Want to See in Your Gas Chromatogram

By Tony Taylor

Sometimes troubleshooting a separation can rely upon the end user spotting subtle clues within the chromatogram, and at other times the visual signs can be much more obvious. To start the New Year, I wanted to share some of the most common issues that we see with peak shapes in gas chromatography in the hope that if you spot some of these in your own work, you may be able to intercept problems and deal with them more effectively.

The LCGC Blog: MS Identification of Microorganisms in Groundwater Near Unconventional Oil and Gas Extraction

By Kevin A. Schug

Two things were surprising about some recent research we reported. First, with regard to chemically impaired groundwater quality, it may not always be the chemicals that are most worrisome for human health impacts. Second, the primary methodology we used in that work for microorganism identification, matrix-assisted laser desorption–ionization mass spectrometry (MALDI-MS), is a vastly underappreciated tool, especially outside the clinical realm in areas such as environmental monitoring.

Celebrating 35 Years


Latest News

Tackling Chagas Disease With Proteomics and LC–MS/MS

Researchers have developed a proteomics‑based approach, using liquid chromatography tandem mass spectrometry (LC–MS/MS), to identify the food sources of the Chagas disease vector Triatominae insects.

Biotage Acquires Horizon Technology

Biotage AB (Uppsala, Sweden) has agreed a deal to purchase all outstanding shares in Horizon Technology Inc. for $18.4 million.


Getting Started with GC Analysis for Cannabis

Wednesday, January 31st, 2018 

1:00 pm EST / 12:00 pm CST / 10:00 am PST / 4:00 pm CEST

Address the Paradigm Shift in Regulatory Inspections

Wednesday, February 28th, 2018 

11:00 am EST / 8:00 am PST / 4:00 pm GMT / 5:00 pm CET

More Upcoming and On Demand Webcasts>>

LCGC eBooks

Powerful Pesticide and Food Allergen Analysis with High Resolution Mass Spectrometry
In this LCGC ebook, experts discuss the use of high-resolution accurate mass (HRAM) as an important way to improve food testing analysis.

Go to eBook Library



HPLC Mobile Phases – 10 bad habits to avoid

The 10 bad habits to avoid when producing HPLC mobile phases.

10 Ways to Break Your LC-MS

If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”. Keep contamination to a minimum and you’ll enjoy a reliable instrument; don’t take the necessary precautions and instead you’ll enjoy reaching for the vent switch and purchasing lots of spares.

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