Where Separation Science is Heading: Quotes

Celebrating 25 Years of LCGC Cover
Quotes from leading separation scientists on the future of separation science and the challenges that must be addressed.


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Featured LCGC Interviews

The Art of Museum Conservation Using Solid-Phase Microextraction–Gas Chromatography–Mass Spectrometry

The Column spoke to Katherine Curran, a lecturer in Sustainable Heritage at the UCL Institute for Sustainable Heritage in London, UK, about her work classifying museum artefacts using volatile organic compound (VOC) analysis and solid-phase microextraction–gas chromatography–mass spectrometry (SPME–GC–MS).

Evaluating Marine Algae for Therapeutic Effects

Snezana Agatonovic-Kustrin, a professor in pharmaceutical chemistry at Monash University, in Kuala Lumpur, Malaysia, spoke to The Column about the development of a method to evaluate antidiabetic and antioxidant activity in marine algae using high-performance thin-layer chromatography (HPTLC)-direct bioautography.

Gas Chromatography

Injecting Water onto a GC Column: Solving the Mystery of Poor Chromatography

By Chris English

Ethylene glycol is a particularly difficult compound to analyze because it is not easily extracted from water. Many environmental samples originate from water runoff at airports, where ethylene glycol is used as a de‑icing agent for airplanes during winter months. Hydraulic fracturing is a technique where pressurized fluid and sand or other solids (proppant) are used in gas drilling to allow gas extraction. Glycols are a common ingredient in most hydraulic fracturing fluid and play a key role in preventing emulsifications and stabilizing the solutions. The direct aqueous injection of ethylene glycol is challenging because it can be difficult to attain reproducibility and good peak shape. The large expansion volume of water can cause backflash, carryover can cause inconsistent results, and excess water can extinguish the flame ionization detection (FID) flame. This article describes a robust approach to analyze glycols in aqueous samples, which reduces downtime and maintains sensitivity.

Trends and Developments

By LCGC Editors

A snapshot of key trends and developments in the chromatography sector according to selected panellists from companies who exhibited at Analytica 2018.

Mass Spectrometry

Headspace Solid-Phase Microextraction Coupled with Gas Chromatography–Mass Spectrometry for the Characterization of Polymeric Materials

By Peter Kusch

HS-SPME-GC–MS is a valuable technique for identifying volatile organic compounds, additives, and degradation products in industrial rubber, car labeling reflection foil, and bone cement materials.

Recent Advances in Comprehensive Chromatographic Analysis of Emerging Drugs

By Ira S. Lurie, Lauriane Tremeau-Cayel, Walter F. Rowe

To address the challenges of analyzing new illicit drugs, emerging techniques such as UHPSFC with MS and UV detection, and GC with VUV detection, may be needed, particularly for distinguishing positional isomers and diastereomers.

Sample Preparation

Trends and Developments

By LCGC Editors

A snapshot of key trends and developments in the chromatography sector according to selected panellists from companies who exhibited at Analytica 2018.

Recent Advances in Solid-Phase Microextraction, Part I: New Tricks for an Old Dog

By Douglas E. Raynie

A look at recent advances in SPME, such as increasing the sorbent surface area available for extraction, accommodating direct analysis by mass spectrometry, and sorbent overcoating to resist fouling by sugars and lipids

Partner Organizations

Chinese American Chromatography Association (CACA)

About CACA



ChromAcademy Homepage


The LCGC Blog: Understanding Stationary Phases for HILIC Separations

By Tony Taylor

HILIC is not straightforward and there may be a number of mechanisms in play which need to be considered.

The LCGC Blog: Quantitative Analysis Using Hybrid Mass Analyzers: Mass Accuracy Versus Tandem Mass Spectrometry

By Kevin A. Schug

What type of mass spectrometry (MS) instrumentation provides the best specificity during trace quantitative analysis from complex mixtures?

Celebrating 35 Years


Latest News

Investigating the Flavour Profiles of E-Cigarettes

Researchers from Gdansk University of Technology, Poland, have investigated the flavour profiles of e-cigarette refill solutions using GC–MS/MS.

LabConnect Expands

LabConnect LLC, a global provider of central laboratory and support services for biopharmaceutical, medical device, and contract research organization, has completed phase one of a 11,000 square foot facility expansion in Johnson City, Tennessee, USA.


Address the Paradigm Shift in Regulatory Inspections

Thursday, May 17th, 2018

9:00 am EDT / 3:00 pm CEST / 6:30 pm IST

Determination of Essential and Trace Elemental Content in Infant Foods by ICP-MS

North America Broadcast: Friday, May 18th, 2018 at 11:00 am EDT / 8:00 am PDT / 4:00 pm BST / 5:00 pm CEST

Europe & Asia Pacific Broadcast: Monday, May 21st, 2018 at 10:00 am BST / 11:00 am CEST / 8:30 am IST / 11:00 am CST/ 12:00 pm JST

More Upcoming and On Demand Webcasts>>

LCGC eBooks

Miniaturized Analytical Equipment Solves Key Challenges for Laboratories
Sometimes, great solutions for analytical laboratories come in small packages. This ebook highlights the important role that miniaturized instruments play in addressing challenges faced by laboratories.

Go to eBook Library



HPLC Mobile Phases – 10 bad habits to avoid

The 10 bad habits to avoid when producing HPLC mobile phases.

10 Ways to Break Your LC-MS

If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”. Keep contamination to a minimum and you’ll enjoy a reliable instrument; don’t take the necessary precautions and instead you’ll enjoy reaching for the vent switch and purchasing lots of spares.

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