Slideshow

Where Separation Science is Heading: Quotes

Celebrating 25 Years of LCGC Cover
Quotes from leading separation scientists on the future of separation science and the challenges that must be addressed.

 

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Featured LCGC Interviews

Determining Chloride and Sugars in Food Samples Using HPLC

Accurate quantification of sugars in saline solution is now possible using a new high performance liquid chromatography (HPLC) method. The Column spoke to Abdelrahman Saleh Zaky from the School of Biosciences at the University of Nottingham (Nottingham, UK) about this method.

Recent Developments in Microchip Electrophoresis

Capillary electrophoresis (CE) is routinely used for chemical and biochemical analysis methods, and recently the technique has been implemented on microchips. R. Scott Martin, a professor and chair of chemistry at Saint Louis University, has been investigating ways to improve these techniques for years. He recently spoke to us about his research coupling microchip electrophoresis with electrochemical detection, coupling continuous flow with microchip electrophoresis with valving, coupling microchip CE with microdialysis sampling and electrochemistry, and more.

Gas Chromatography

Results Correlation with External Influences

By John V. Hinshaw

When data change over time, you may be able to tease out the causes by conducting a time-series analysis or by looking at various forms of correlation.

The Secrets of Successful Temperature Programming

By Dawn Wallace Watson

A quick step-by-step guide for optimizing GC temperature programming.

Mass Spectrometry

Celebrating 35 Years of LCGC

By The Editors of LCGC

Leading separation scientists share their perspectives on current challenges in separation science and where the field is heading. Click the title to view the full article.

New Advice on an Old Topic: Buffers in Reversed-Phase HPLC

By Sharon Lupo, Ty Kahler

A model set of analytes and selected applications are used to demonstrate the effects that buffers can have on the selectivity of a separation and the sensitivity of a reversed-phase analysis when using MS detection.

Sample Preparation

Electrophoretic Concentration—A Simple and Green Approach for Sample Preparation

By Alain Wuethrich, Paul R. Haddad, Joselito P. Quirino

We explain the principles of EC and demonstrate its use to enrich anionic pollutants and cationic drugs in environmental samples.

Partner Organizations

Sepu, China's Largest Chromatography Training Site

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Chinese American Chromatography Association (CACA)

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ChromAcademy

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LCGC Blog

The LCGC Blog: Dwell Volume – Still Relevant in our UHPLC World?

By Tony Taylor

With the increasing proliferation of UHPLC, with its very much reduced extra column volumes, is the concept of dwell volume still relevant? Indeed, in your world, was it ever relevant at all?

The LCGC Blog: Reflecting on 12 Years as a Chemistry Professor

By Kevin A. Schug

As the fall semester starts, I begin my 13th year as a chemistry professor. Let me get right to the point—if you do not love this job, you will hate it!

Celebrating 35 Years

 

 

LCGC TV

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Latest News

Investigating the Effectiveness of Caviar in Cosmetic Skin Creams

Researchers from the University of Torino have developed a novel HPLC–HRMS application for evaluating cosmetic ingredient composition. The application was used to analyze and compare sturgeon eggs, commonly known as caviar, and brill eggs, and their use in beauty creams as lipid sources.

Metabolomic Pathway Analysis of Schizophrenic Brains

Researchers from the Japanese Institute of Neuroscience have identified differences in the low-molecular-weight metabolite profiles of the brains of schizophrenia patients using CE–TOF-MS.

Webcasts

Maximizing Return for Routine Environmental Analysis Part 1: Updating Outdated SVOC Instrumentation

Thursday, September 7th, 2017 

11:00 am EDT / 08:00 am PDT / 4:00 pm BST / 5:00 pm CEST

 

Real-Time, Comprehensive Ambient and Fenceline Monitoring Using Direct MS

Thursday, September 21st, 2017 

11:00 am EDT / 8:00 am PDT / 4:00 pm BST / 5:00 pm CEST

More Upcoming and On Demand Webcasts>>

LCGC eBooks

Advances in Biopharmaceutical Characterization
In this eBook, readers will gain insight into the evolution and future of Orbitrap-based mass spectrometry systems straight from the inventor of this technology, Alexander Makarov, PhD, director of global research LSMS at Thermo Fisher Scientific.

Go to eBook Library

 

CHROMacademy

HPLC Mobile Phases – 10 bad habits to avoid

The 10 bad habits to avoid when producing HPLC mobile phases.

10 Ways to Break Your LC-MS

If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”. Keep contamination to a minimum and you’ll enjoy a reliable instrument; don’t take the necessary precautions and instead you’ll enjoy reaching for the vent switch and purchasing lots of spares.

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