Gas chromatography–atmospheric pressure chemical ionization (GC–APCI) offers increased limits of sensitivity in food analysis. Carlos Sales Martinez from the Research Institute of Pesticides and Water in the University Jaume I, Castellón, Spain, has been exploring the novelty of this technique for the analysis of food samples. He recently spoke to LCGC about this work.
By LCGC Editors
Affinity separations offer great potential for pharmaceutical analysis.
An investigation into the root cause of new peaks revealed an unusual source of contamination.
By Jack Cochran
Jack Cochran’s new column “Practical GC” aims to provide readers with practical advice and new experimental evidence for how to get the best results from their gas chromatography (GC) systems. The first article in a series on split injection GC focuses on the advantages of using “shoot-and-dilute” GC.
Dead-volume effects can cause serious trouble for chromatographers. But if you understand what dead volume is and how it affects chromatographic results, you can take control of it.
By LCGC Editors
Imaging techniques using vibrational spectroscopy, MS, and atomic force microscopy have all been advancing and gaining momentum in recent years. There is great potential power in these imaging techniques, particularly in the biomedical field. Here, Thomas Bocklitz of the Friedrich-Schiller- University Jena discusses his work combining these techniques.
The power of nontargeted metabolite profiling is illustrated in a study focused on the determination of molecular markers in malting barley.
Is your swimming pool clean and safe? Recreational water illness, most commonly in the form of digestive tract illness or skin, ear, or respiratory infections, is often caused by water contamination. The authors present a robust method, using solid-phase extraction and high-resolution mass spectrometry, for monitoring swimming pool water.
A survey of LCGC readers on sample preparation techniques and methodology investigated trends in technologies being used, sample loads, sample sizes, automation, the use of SPE devices (cartridges, disks, plates, tips), SPE chemistries, selection criteria, and problems encountered.
By LCGC Editors
This first installment of the “Sample Prep Perspectives” column presents an overview of the primary manual and automated sample preparation techniques—methods that are much the same as those in use today.
As expected, the new products introduced in the past year in the area of chromatographic sample preparation, while somewhat limited, mirror the current development in the field.
By Tony Taylor
Some modern HPLC systems resemble spacecraft in terms of their technology, designed as they are to operate to the highest efficiencies, compared to traditional systems. However, I still see countless examples where high efficiency columns are used on systems which are not matched and cannot support the highest efficiencies offered by the column.
After 10 years at U.T. Arlington, I have decided it is time to take one of the best opportunities afforded to researchers in an academic faculty position—to travel abroad and assimilate new techniques into my repertoire to enhance future research activities.
Seven outdated traditional practices that should not be performed without considering alternative approaches that can improve results, provide lower operation costs, or give faster run times. Instead of working harder, analytical scientists should work smarter. Learn more by clicking through the slideshow.
Webster’s New Collegiate Dictionary defines a myth as “an ill-founded belief held uncritically, especially by an interested group.” Could that group be misinformed chromatographers?
Researchers from Imperial College London and the University of Aberdeen have identified disease markers for Human African Trypanosomiasis (HAT), commonly known as “sleeping sickness”. Using reversed-phase ultrahigh‑performance liquid chromatography coupled to mass spectrometry (UHPLC–MS) and proton nuclear magnetic resonance (1H NMR) spectroscopy researchers found 53 discriminatory metabolite markers.
A team of researchers based in France has examined the consequences of microwave and electron-beam treatments on food and its packaging using high performance liquid chromatography (HPLC) and gas chromatography (GC)
A team of researchers based in France has examined the consequences of microwave and electron-beam treatments on food and its packaging using high performance liquid chromatography (HPLC) and gas chromatography (GC).
Anti-histamines and compounds used to medicate anxiety and seizures were among those identified in grocery market fish fillets using a novel gas chromatography–mass spectrometry (GC–MS) technique.
LGC (London, UK) has announced its acquisition of Maine Standards Company (Cumberland Foreside, Maine, USA).
Tuesday, January 26, 2016 11am EDT/ 8am PDT/ 4pm BST/ 5pm CEST
Thursday, February 11th, 2016
8 am CST / 9 am EST / 2 pm GMT / 3 pm CET
Wednesday, February 24th, 2016
8 am PST / 10 am CST / 11am EST / 4 pm GMT / 5 pm CET
This e-book, based on a series of four web seminars, provides pesticide residue analysts with valuable information from Thermo Fisher Scientific about the development and optimization of methods and workflows for the analysis of pesticide residues in food.
They say a picture paints a thousand words…This month I’ve taken inspiration from a recent webcast, presented at www.chromacademy.com, in which I presented real data from our work that represents some ‘classic’ GC problems.
Static headspace sampling is typically used for the determination of volatile and semi-volatile analytes in liquids and, more rarely, solid matrices. Application examples include the analysis of alcohols in blood, residual solvents in pharmaceuticals, flavours and taints in food and beverages as well as fragrances in perfumes and detergents.