Slideshow

Where Separation Science is Heading: Quotes

Celebrating 25 Years of LCGC Cover
Quotes from leading separation scientists on the future of separation science and the challenges that must be addressed.

 

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Featured LCGC Interviews

Determining Chloride and Sugars in Food Samples Using HPLC

Accurate quantification of sugars in saline solution is now possible using a new high performance liquid chromatography (HPLC) method. The Column spoke to Abdelrahman Saleh Zaky from the School of Biosciences at the University of Nottingham (Nottingham, UK) about this method.

Recent Developments in Microchip Electrophoresis

Capillary electrophoresis (CE) is routinely used for chemical and biochemical analysis methods, and recently the technique has been implemented on microchips. R. Scott Martin, a professor and chair of chemistry at Saint Louis University, has been investigating ways to improve these techniques for years. He recently spoke to us about his research coupling microchip electrophoresis with electrochemical detection, coupling continuous flow with microchip electrophoresis with valving, coupling microchip CE with microdialysis sampling and electrochemistry, and more.

Gas Chromatography

Fast Gas Chromatography

By John V. Hinshaw

Fast gas chromatography (GC) has received new attention recently in the form of available enhanced instrument capabilities. What can fast GC do for separations, and how can laboratories take advantage of enhanced separation speeds?

Analyzing Chemical Secretions in Lizards Using GC–MS/MS

By LCGC Editors

The chemical messages that animals use to communicate can trigger a range of responses in members of the same species. The Column spoke to Jorge Saiz from the Centre of Metabolomics and Bioanalysis (CEMBIO) at the University San Pablo CEU, Spain, about his research into the chemical secretions of lizards and the role of gas chromatography–tandem mass spectrometry (GC–MS/MS) in his work.

Mass Spectrometry

Analysis of Next-Generation Protein Biopharmaceuticals

By Dawn Wallace Watson

Tips for effective use of chromatography and mass spectrometry for the analysis of antibody–drug conjugates, glycoengineered proteins, and biosimilars.

Haloacetic Acid Analysis Using Two-Dimensional Matrix-Elimination Ion Chromatography

By Rong Lin, Herb Wagner, Carl Fisher, Kannan Srinivasan, Chris Pohl

The disinfectants commonly used to treat public drinking water can react with naturally occurring organic and inorganic matter in the source water to form disinfection byproducts such as haloacetic acids. Here, we describe the use of two-dimensional matrix-elimination ion chromatography (MEIC) for haloacetic acid analysis. This method minimizes the impact of matrix ions.

Sample Preparation

Analysis and Fate of Surfactants in the Aquatic Environment

By LCGC Editors

According to Analysis and Fate of Surfactants in the Aquatic Environment (Volume 40 of Wilson & Wilson's Comprehensive Analytical Chemistry), an understanding of the fate and behaviour of organic chemicals, such as surfactants?

Partner Organizations

Sepu, China's Largest Chromatography Training Site

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Chinese American Chromatography Association (CACA)

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ChromAcademy

ChromAcademy Homepage
 

LCGC Blog

The LCGC Blog: Underutilized Methods for Optimizing LC–MS Sensitivity

By Tony Taylor

I hear the words “struggling for sensitivity” so often when speaking to folks using LC–MS for bioanalysis, environmental analysis, metabolomics, proteomics, and a host of other applications where target analytes are present at low concentrations in complex matrices. We spend fortunes on MS/MS instruments to increase specificity of detection in order to improve sensitivity. Some of us go to great lengths to optimize sample extraction and HPLC conditions in order to minimize matrix suppression effects and improve specificity and hence sensitivity.

The LCGC Blog: Pesticide Analysis in Cannabis: Choosing the Right Technique

By Doug D. Carlton, Jr.

The presence of capable students and researchers, each with a technical niche to offer, prepares us for future opportunities. On top of that structure, we also aim to maintain this mindset for our instrument selection before beginning projects. The installment of core labs at UT Arlington (www.uta.edu/sirt), making a wide range of instruments available to all research groups, has allowed our students to brainstorm about which instrument is the most appropriate for a specific analysis rather than how to make a measurement work with a given instrument.

Celebrating 35 Years

 

 

LCGC TV

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Latest News

Gerstel Celebrates 50 Years

Gerstel GmbH & Co. KG celebrated its 50th anniversary this year and to mark the occasion hosted a gala event open to its staff and partners from across the globe.

Webcasts

High-Throughput Analysis of Volatile Emissions From Packaging, Polymers, and Natural Materials Using Direct MS

Wednesday, November 29th, 2017 

2:00 pm EST / 1:00 pm CST / 11:00 am PST / 5:00 pm CEST

High Resolution Accurate Mass- and Triple Quadrupole-LCMS Workflows for Todays Veterinary Drugs Testing Laboratories

Thursday, November 30th, 2017 

11:00 am EST / 8:00 am PST / 4:00 pm GMT / 5:00 pm CET

More Upcoming and On Demand Webcasts>>

LCGC eBooks

Water Purification in the Chromatography Lab
In Water Purification in the Chromatography Lab (sponsored by Millipore Sigma), experts offer numerous practical tips for lab water purification, handling, and purification system selection. 

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CHROMacademy

HPLC Mobile Phases – 10 bad habits to avoid

The 10 bad habits to avoid when producing HPLC mobile phases.

10 Ways to Break Your LC-MS

If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”. Keep contamination to a minimum and you’ll enjoy a reliable instrument; don’t take the necessary precautions and instead you’ll enjoy reaching for the vent switch and purchasing lots of spares.

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