Jobs in Analytical Chemistry

You may have an excellent educational background, and perhaps some very good experience, too. But are you prepared to get—and keep—your next job in analytical chemistry? This collection of short articles from LCGC’s digital magazine, The Column, offers essential advice for separation scientists who aspire to get a new job and succeed once there.

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Featured LCGC Interviews

The Heightened Role of HILIC in Biopharmaceutical Analysis

Valentina D’Atri from the University of Geneva spoke to The Column about the evolving role of HILIC in biopharmaceutical analysis.

Investigating Cheetah Metabolite Profiles Using GC–MS

Adrian Tordiffe from the Veterinary Faculty of the University of Pretoria in South Africa, is working to establish baseline metabolic profiles for captive and free-ranging cheetahs to investigate the unusual medical conditions that the animals develop in captivity. He spoke to The Column about his work and about the role that chromatography plays.

Gas Chromatography

Effects of External Influences on GC Results

By John V. Hinshaw

If you understand how your system is affected by outside influences, you can take control of the variables.

New Gas Chromatography Products for 2016–2017

By John V. Hinshaw

Annual review of new developments in the field of GC

Mass Spectrometry

New Advice on an Old Topic: Buffers in Reversed-Phase HPLC

By Sharon Lupo, Ty Kahler

A model set of analytes and selected applications are used to demonstrate the effects that buffers can have on the selectivity of a separation and the sensitivity of a reversed-phase analysis when using MS detection.

Analysis of Organic Compounds in Water Using Unique Concentration–Injection Techniques for Portable GC–MS

By Tai V. Truong, Thy X. Truong, Nathan L. Porter, Edgar D. Lee, Milton L. Lee

In this study, a simple method was used for extraction and concentration of trace organic compounds in water, followed by injection using a coiled wire filament and GC–MS analysis. Common semivolatile organic compound contaminants at low parts-per-billion levels were detected in less than 10 min.

Sample Preparation

Electrophoretic Concentration—A Simple and Green Approach for Sample Preparation

By Alain Wuethrich, Paul R. Haddad, Joselito P. Quirino

We explain the principles of EC and demonstrate its use to enrich anionic pollutants and cationic drugs in environmental samples.

The Use of Extraction Technologies in Food Safety Studies

By Doug Raynie, Changling Qiu

New extraction techniques can improve the accuracy and precision of analytical results and simplify analytical procedures.

Partner Organizations

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The LCGC Blog: Hydrophilic Interaction Chromatography - Practical Insights

By Tony Taylor

Hydrophilic Interaction Chromatography can be a very useful tool in our analytical armory, however there are some practical peculiarities to this chromatographic mode which need to be understood in order to ensure success. 

The LCGC Blog: Intact Protein Ion Transmission in a Triple-Quadrupole Mass Spectrometer

By Kevin A. Schug

I believe that the term “top-down proteomics” holds a particular connotation with respect to the use of ultrahigh-resolution mass spectrometers in people’s minds. And rightfully so. If one is to determine with confidence the sequence and charge state of a particular fragment ion generated in the gas phase, then high mass accuracy is a must. From the discovery side of things, where qualitative analysis is most important, this is not likely to change. However, when you turn to quantitative analysis, where you want to now monitor levels of a particular protein biomarker for the purpose of disease diagnosis, prognosis, or treatment, then invariably bottom-up strategies are the norm. Protein quantitation using top-down strategies, especially on low-resolution triple-quadrupole systems, have been largely ignored, until recently.

Celebrating 35 Years




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Latest News

Gary Patti Receives Agilent’s Early Career Professor Award

Gary J. Patti is the recipient of the 2017 Agilent Early Career Professor Award.

MiliporeSigma Bader Award Now Accepting Submissions

MilliporeSigma (St. Louis, Missouri, USA) is now accepting entries for the Alfred R. Bader Award for Student Innovation.


Best LC Practices for Efficient Lab Operations Part 1: Getting the Most Out of your LC Systems

Tuesday, July 11th, 2017 

11:00 am EDT / 08:00 am PDT / 4:00 pm BST / 5:00 pm CEST


Orbitrap GC-MS: An Opportunity to Help Address the Challenges of Chlorinated Paraffins Analysis

Wednesday, July 12th, 2017 

11:00 am EDT / 8:00 am PDT / 4:00 pm BST / 5:00 pm CEST

More Upcoming and On Demand Webcasts>>

LCGC eBooks

Practical Coploymer Analysis Using GPC/SEC and Related Techniques
In this eBook, experts discuss how several GPC/SEC methods may improve copolymer sample characterization. Learn about dual-detection methods, polymer liquid adsorption chromatography, 2D chromatography, and more.

Go to eBook Library>>



HPLC Mobile Phases – 10 bad habits to avoid

The 10 bad habits to avoid when producing HPLC mobile phases.

10 Ways to Break Your LC-MS

If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”. Keep contamination to a minimum and you’ll enjoy a reliable instrument; don’t take the necessary precautions and instead you’ll enjoy reaching for the vent switch and purchasing lots of spares.

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