Application Notes: LC/HPLC

Feb 02, 2018
Sponsored Content - EU
Self-association is crucial for regulation of certain kinase proteins. However, a kinase fragment that lacks the oligomerization domain is still dimeric in solution, as determined by SEC-MALS in this note.
Feb 02, 2018
Sponsored Content - EU
Host-guest complexes constitute transient conjugates that are quite stable due to mechanical incorporation of the guest into the hollow host molecule. Multi-angle light scattering (MALS) and asymmetric field-flow-fractionation (AF4) determine the heteroternary stoichiometry and stability of such a complex.
Feb 02, 2018
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This white paper explains how multi-angle light scattering (MALS) and intrinsic viscosity detectors, coupled to size-exclusion chromatography or field-flow fractionation, are used to fully characterize branched polymers.
Feb 02, 2018
Sponsored Content - EU
Sodium alginate is a food thickening agent that may be irradiated for sterilization. In this note, changes in biopolymer molar mass and conformation which impact macroscopic properties are analyzed by SEC-MALS.
Feb 02, 2018
Sponsored Content - EU
This white paper explains how multi-angle light scattering (MALS) and intrinsic viscosity detectors, coupled to size-exclusion chromatography or field-flow fractionation, are used to fully characterize branched polymers.
Feb 02, 2018
Sponsored Content - EU
Size exclusion chromatography combined with multi-angle light scattering and intrinsic viscosity enables absolute determination of the molecular weight, size and conformation of hyaluronic acid, which exhibits inherent stiffness and non-Gaussian chain behavior at low molar masses.
Feb 02, 2018
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Conventional GPC could not accurately analyze the molecular weight of N3-PS-PEO-PS-N3 produced by “click” chemistry. Triple-detection SEC is required for this sample incorporating multiple blocks within a single polymer chain.
Feb 02, 2018
Sponsored Content - EU
Co-polymers cannot be characterized by standard GPC. A triple-detection method, incorporating multi-angle light scattering (MALS), UV and RI measurement is shown to provide complete characterization including molar mass co-polymer composition.
Feb 02, 2018
Sponsored Content - NA
Size exclusion chromatography combined with multi-angle light scattering and intrinsic viscosity enables absolute determination of the molecular weight, size and conformation of hyaluronic acid, which exhibits inherent stiffness and non-Gaussian chain behavior at low molar masses.
Feb 02, 2018
Sponsored Content - NA
Co-polymers cannot be characterized by standard GPC. A triple-detection method, incorporating multi-angle light scattering (MALS), UV and RI measurement is shown to provide complete characterization including molar mass co-polymer composition.
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