Seeing the Big Picture: Multidimensional Liquid Chromatography for Biotherapeutic Characterization

Discover the supremacy of the bioinert coated hardware of YMC Accura BioPro IEX QF columns for reproducible analysis of oligonucleotides in ion-exchange chromatography.

We show the development of HPLC-ELSD methods for high-throughput and sensitive analysis of the lipids in lipid nanoparticles (LNPs), used to administer mRNA vaccines.

Recycling chromatography is a powerful technique that allows the separation of two closely eluting peaks by increasing the column bed length.

KNAUER AZURA UHPLC system, thanks to the low dispersion and operating pressure up to 1240 bar, allows to speed up your method and increase throughput preserving resolution

Trifluoroacetic acid (TFA) as an eluent modifier causes baseline ripples, with negative effect on LOD/LOQ. This can be mitigated by adjusting the pump mixer volume

The KNAUER HPLC Method Converter assists you to modernize the analytical method according to the allowed variations last US and EU Pharmacopeia (USP) chapter 621