Determination of Adenine and Guanine Nucleotides
The measurement of adenosine nucleotides represents important diagnostic measures concerning metabolic standing for the determination of various pathological states.
Separation of Fat-Soluble Vitamin K Congeners
The coagulation benefits of vitamin K1 are well known, however, the other congeners of the vitamin series are not as common (K2, K3, and K4), but equally contribute to a healthy disposition.
Poisoned by Plastic: Analysis of BPA (Nov 2023)
Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.
Legumes – Blessing and Curse (Nov 2023)
Discover how the HC-75 series uses a ligand exchange mechanism in order to interact more or less strongly with the analytes of interest.
Oligonucleotide Purification by Reversed-Phase Ion Pairing (Nov 2023)
Hamilton's PRP-C18 column gave good separation with various gradient profiles and under various particle sizes. The excellent loading capacity of the column make this stationary phase desirable.
Separating 12 Nucleosides on Hamilton Column
Modified nucleosides, either natural or synthetic, often provide RNA with distinctive properties useful in diagnostics or therapeutics.
Separation of Fat-Soluble Vitamin K Congeners in Under 6 Minutes
A fast, simple method using the PRP-C18 column allows for simple, efficient identification of the natural and synthetic compounds of vitamin K (K2, K3, and K4).
Arsenic Speciation on Hamilton PRP-X100 (Oct 2023)
Contamination of drinking water and food sources is of great concern. Isolation and quantification of the various arsenic states is identified.
Isolation of Capsaicin for Therapeutic Treatments (Oct 2023)
Isolation of capsaicin for medicinal uses is easily achieved with the PRP-C18 RP-HPLC resin.
Isoflavones and Mycotoxins in Soy Beans (Oct 2023)
Analyzing crops for beneficial and harmful compounds is an indispensable tool for assessing the viability of various agricultural crops for consumption.
Determination of Flavonoids in Hemp (Oct 2023)
Flavonoids in cannabis, fruits and vegetables protect plants. Hamilton has developed a method to confirm the 7 most common flavonoids in cannabis with the PRP-1 column.
Separation of Halo Acetic Acids by Ion Exclusion (Oct 2023)
Accurate detection of HAAs is paramount for prevention of overoxidation while still managing enough water sanitation to eliminate water-borne pathogens.
Separation of Basic Drug Compounds (Sept 2023)
In this study, a generic, 5-min linear gradient was used to separate six basic drug compounds on a short (50 mm) PRP-C18 column.
Spill the Tea, Catechin Identification (Sept 2023)
Identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products.
Separation of Strongly Basic Drug Compounds (Sept 2023)
Nine structurally diverse, strongly basic drug compounds are resolved in less than 2 minutes using a high pH mobile phase and a fast acetonitrile gradient at 80 °C.
Pick Your Poison: Isolation of Paclitaxel Sept 2023)
The diterpenoid, paclitaxel, is as a potent chemotherapy agent for breast and ovarian cancer. Here, the isolation of paclitaxel from its major impurities is shown.
Flexible Anion Analysis with Hamilton Columns (Sept 2023)
Chemically resistant resin bed allows for a wide base of mobile phase choices with excellent anion separation
Separation of Common Benzodiazepine Metabolites (Sept 2023)
Identifying benzodiazepine metabolites can be highly valuable in detecting abuse. Metabolites of oxazepam are found containing both hydroxyl and glucuronides.
Separation of Five Steroids (Sept 2023)
A reversed-phase HPLC method was developed to separate five steroid hormones, with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone).
Allergens in Peruvian Essential Oil, Balsam
Despite the utility of the essential oil mixture, it has been shown that allergies can arise from some of the individual components.
Separation of Strongly Basic Drug Compounds (May 2023)
Nine structurally diverse, strongly basic drug compounds are resolved in less than 2 minutes using a high pH mobile phase and a fast acetonitrile gradient.
Flexible Anion Analysis with Hamilton Columns
Spill the Tea, Catechin Identification (May 2023)
This focuses on the identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products.
Pick Your Poison. Isolation of Paclitaxel (May 2023)
The isolation of the diterpenoid, paclitaxel, from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.
Separation of Five Steroids (May 2023)
A reversed-phase HPLC method was developed for separation of five steroid hormones with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone).
Separation of Basic Drug Compounds (May 2023)
Separation of Selected Ylang-Ylang Oil Components
Isolation of six common allergens can be achieved by utilizing reversed-phase HPLC using an alkaline eluent.
Separation of Common Benzodiazepine Metabolites (May 2023)
The identification benzodiazepine metabolites can be highly valuable in detecting abuse. Metabolites of oxazepam are found containing both hydroxyl and glucuronides.
Biologically Active Increasing Length Peptides (May 2023)
This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.
Oligonucleotide Purification by Reversed-Phase Ion Pairing (May 2023)
A Hamilton PRP-C18 (5 μm) HPLC column was used for purifying three oligonucleotides. Analysis of a 21mer, 22mer, and 23mer of similar structure were evaluated.