May 13th 2024
In this edition of The LCGC Blog, Katelynn Perrault and James Harynuk discuss the technological needs one faces when setting up a workstation for chromatography data analysis.
Non-Classical Methods in Comprehensive Two-Dimensional Gas Chromatography
March 1st 2007It may be somewhat audacious to claim that some methods in GCÃ-GC can be called non-classical - the technique has only been around for about 15 years and one might argue that this is not long enough to establish a suite of classical methods.
How Close is Close Enough? Accuracy and Precision
March 1st 2007The accuracy and precision of results in gas chromatography and other analytical techniques are highly dependent upon the sample and its preparation, the instrumentation, accessories and operating conditions, as well as operator skill and experience. For these reasons, accuracy and precision for a specific methodology can be expected to vary from one laboratory or operator to another. This month, we look at statistical analysis as a diagnostic tool.
Setting Realistic Expectations for GC Optimization
March 1st 2007Setting realistic expectations requires a good working knowledge of an instrument's capabilities in terms of the sample requirements as well as an understanding of the effects of real-world samples and their matrices on long-term instrument performance.
Separation Instrumentation Demand
March 1st 2007Separation instrument techniques are among the most widely used technologies in the analytical instrumentation market. They span the entire industrial and regional marketplace. The lab separations market includes chromatographic techniques such as analytical and preparative HPLC, GC, IC, TLC, flash, and low pressure LC.
Gas Chromatography?Time-of-Flight Mass Spectrometry in Food Analysis
March 1st 2007Gas chromatography (GC) coupled to time-of-flight mass spectrometry (TOF-MS) offers unique solutions for various analytical applications including the analysis of food quality, authenticity and safety markers. This article provides a general overview of TOF-MS basic features, highlighting its advantages and limitations compared with GC using conventional mass analyzers. Examples of recent results obtained for selected food contaminants and flavor components are described to illustrate the potential of this recently introduced technique.
Gas Chromatography-Time-of-Flight Mass Spectrometry in Food Analysis
March 1st 2007Gas chromatography (GC) coupled to time-of-flight mass spectrometry (TOF-MS) offers unique solutions for various analytical applications including the analysis of food quality, authenticity and safety markers. This article provides a general overview of TOF-MS basic features, highlighting its advantages and limitations compared with GC conventional mass analyzers. Examples of recent results obtained selected food contaminants and flavor components are described illustrate the potential of this recently introduced technique.
LC-MS in Evironmental, High-Throughput, and Other Applications
February 25th 2007Eight presentations on a variety of LC-MS applications were given in Session 170 on this first afternoon at Pittcon. One of the most interesting was session 170-6, "Techniques of LC-MS in Forensics Analysis." The speaker, Michael C. Zumwalt, discussed the variety of LC-MS instrumentation available to meet both qualitative and quantitative needs. Among the interesting applications he discussed were those for detecting drugs of abuse and explosives. Workplace drug testing and forensic toxicology are examples of these applications. LC-MS continues to be a rapidly growing technique, and the ways in which it can be used in forensic analysis are quite varied. Serial measurement systems are used for quantitation, while parallel systems are best for qualitative applications. Serial systems such as single quadrupole and triple quadrupole mass spectrometers are very useful for detecting drugs of abuse in oral fluids. A particular advantage noted by the speaker is the ease of sample collection, which can even be done in the field, for example, by a police officer.
Problems and Solutions of Landmine and Improvised Explosive Devices
February 25th 2007As most of us traveled by air to Chicago this weekend, we all passed through airport security and the various drills like taking off our shoes, removing metal objects and taking the all-important laptop out of its case.
Liquid Chromatography at the Extreme: Ultra-Pressure, High Temperature, and Ultra-Fast
February 25th 2007Pittcon 2007 opened with a bang here in Chicago, albeit a snowy bang. All the liquid falling outside, whether in rain, snow, or ice form, was nothing compared to the liquid chromatography sessions.
Separation Instrumentation Demand
February 20th 2007Separation instrument techniques are among the most widely used technologies in the analytical instrumentation market. It spans the entire industrial and regional marketplace. The lab separations market includes chromatographic techniques like analytical and preparative HPLC, GC, IC, TLC, flash, and low pressure LC.