Krull and Swartz examine validating cleaning methods for pharmaceutical manufacturing equipment and look at general requirements and specific cleaning procedures, sampling types, and analytical methods.
This month's column looks at validating cleaning methods for pharmaceutical manufacturing equipment. Krill and Swartz discuss general requirements and specific cleaning procedures, sampling types, and analytical methods.
LCGC 17(11), 1016–1019 (1999).Monitoring 5-Fluorouracil Levels in Dried Blood Spots with UHPLC-MS/MS
May 3rd 2024Researchers have utilized ultra-high performance liquid chromatography-tandem mass spectrometry (UH PLC-MS/MS) to monitor 5-Fluorouracil, a medication used to treat various cancers, in dried blood spots. This process offers a simpler, more efficient method than those in place involving the monitoring of plasma.
Vitamin D Determination Tested Using Liquid Chromatography–Tandem Mass Spectrometry
May 2nd 2024Scientists from Hangzhou Medical College recently recorded the effectiveness of novel quality control strategies for the determination of vitamin D using liquid chromatography–tandem mass spectrometry (LC–MS/MS).