Selected highlights from The Columns 2016 archives.
1. Split Injection GC: Inlet Liner Choice for Shoot and Dilute GC
Jack Cochran’s “Practical GC” provided readers with practical advice and new experimental evidence for how to get the best results from their gas chromatography (GC) systems. This instalment looked at GC inlet liner choice for “shoot and dilute” GC.
2. Onshoring Your Insourced Solutions?
Incognito debated the pros and cons of onshore support.
Raquel Garcia and Maria João Cabrita revealed the theory and practical applications of molecularly imprinted polymers (MIPs).
4. Detecting Carcinogens in Water
Koji Kosaka of the National Institute of Public Health, Japan, spoke with The Column about his use of high performance liquid chromatography (HPLC) to uncover the source of contamination in the Yodo River Basin in Japan, with the precursors of the carcinogen N-Nitrosodimethylamine (NDMA).
Protein biopharmaceuticals have seen an enormous growth in the last decade, and as a result, separation scientists are giving increased attention to methods for characterizing biopharmaceuticals. One powerful technique for analyzing proteins is two-dimensional liquid chromatography (2D LC). Gerd Vanhoenacker of the Research Institute for Chromatography (RIC) in Kortrijk, Belgium, spoke to The Column about his research into peptide mapping of therapeutic monoclonal antibodies (mAbs) using 2D LC.
Jean-Luc Veuthey and Alexandre GrandâGuillaume-Perrenoud revealed the latest developments in supercritical fluid chromatography (SFC) that are bringing the technique back to the limelight.
7. FPLC versus Analytical HPLC: Two Methods, One Origin, Many Differences
This article discussed the differences between the two techniques with particular emphasis on the requirements of their respective analytes.
8. Contemporary Trends in Ion Chromatography
Ion chromatography coupled to mass spectrometry (IC-MS) does not follow the same rules as coupling other modes of liquid chromatography to mass spectrometry (LC–MS). Leon Barron from the Analytical & Environmental Science Division, at King’s College London, UK, revealed some of the misconceptions surrounding IC and discussed contemporary trends and novel applications for this inventive technique.
9. The Value of Chemometrics and Experimental Design to Analytical Chemists
Kevin A. Schug considered what the study of chemometrics and experimental design statistics can add to an analytical chemist’s work.
10. System and Column Volumes in HPLC: We Still Haven’t Gotten the Message
What is required to produce a highly efficient modern high performance liquid chromatography (HPLC) system/column combination? This instalment of the LCGC Blog explained more.
Analysis of Greenhouse Gases by Gas Chromatography
May 15th 2024This application note demonstrates the use of SCION's 8500GC system for the analysis of key greenhouse gases—carbon dioxide, methane, and nitrous oxide—in a single atmospheric air matrix. Highlighting the system's excellent sensitivity and repeatability, this method is crucial for understanding emission sources and combating climate change.
Determination of Limonene in Recycled HDPE Pellets
May 15th 2024This application note showcases the SCION 8300 GC with SQ MS's capability to detect limonene in recycled HDPE pellets, emphasizing its high sensitivity and robustness. The method ensures that the recycled pellets, crucial for manufacturing deodorized food packaging, contain limonene concentrations well below the 20ppm threshold, demonstrating the efficacy of the recycling process.