What does risk assessment in the context of the life cycle of a high performance liquid chromatography (HPLC) instrument really mean? This article looks at problems with an operational liquid chromatograph to see if they can be picked up in the performance qualification (PQ) or prevented in the operational qualification (OQ). The relationship between PQ and OQ and the design qualification (DQ) phases of the life cycle are also explored.
Analysis of Greenhouse Gases by Gas Chromatography
May 15th 2024This application note demonstrates the use of SCION's 8500GC system for the analysis of key greenhouse gases—carbon dioxide, methane, and nitrous oxide—in a single atmospheric air matrix. Highlighting the system's excellent sensitivity and repeatability, this method is crucial for understanding emission sources and combating climate change.
Plant Protection Product Impurity Screening by GC-FID with GC-MS Confirmation
May 15th 2024This application note from SCION Instruments delves into the meticulous screening of impurities in plant protection products using GC-FID, with GC-MS for confirmation. It emphasizes the necessity of identifying and quantifying impurities to comply with regulatory standards in industries such as pharmaceuticals, food, and agriculture. The study specifically examines eugenol, showcasing how to determine significant impurities for regulatory submission. The approach integrates GC-MS and analytical standards, ensuring precise impurity identification and quantification critical for product approval.
Determination of Limonene in Recycled HDPE Pellets
May 15th 2024This application note showcases the SCION 8300 GC with SQ MS's capability to detect limonene in recycled HDPE pellets, emphasizing its high sensitivity and robustness. The method ensures that the recycled pellets, crucial for manufacturing deodorized food packaging, contain limonene concentrations well below the 20ppm threshold, demonstrating the efficacy of the recycling process.