This first column of "Drug Discovery" chronicles the development of the drug discovery process and explains how separation technologies fit in the world of drug discovery.
LCGC 18(1), 42–44 (2000).Monitoring 5-Fluorouracil Levels in Dried Blood Spots with UHPLC-MS/MS
May 3rd 2024Researchers have utilized ultra-high performance liquid chromatography-tandem mass spectrometry (UH PLC-MS/MS) to monitor 5-Fluorouracil, a medication used to treat various cancers, in dried blood spots. This process offers a simpler, more efficient method than those in place involving the monitoring of plasma.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.