Vol 33 No1 LCGC North America January 2015 Regular Issue PDF

In this installment, we apply the concepts developed in last month’s installment by demonstrating how they can be used to help troubleshoot problems in LC involving pressure and flow.

Peptides are versatile molecules that have a wide range of applications in biotechnology, medicine, and research. They can be used as drugs, diagnostics, biomarkers, or tools to study cellular processes. However, peptides also pose unique challenges in terms of analysis and purification due to their complexity, diversity, and sensitivity.

Yelena Sapozhnikova from the United States Department of Agriculture spoke to The Column about her innovative research investigating PFAS in plastic food storage bags using targeted and non-targeted liquid chromatography–tandem mass spectrometry.

Selected ion flow tube mas spectrometry (SIFT–MS) offers real-time measurements directly from air without chromatography or sample preparation, providing an attractive alternative for these hard-to-measure volatile organic compounds.