May 8th 2024
Yelena Sapozhnikova from the United States Department of Agriculture spoke to The Column about her innovative research investigating PFAS in plastic food storage bags using targeted and non-targeted liquid chromatography–tandem mass spectrometry.
New Study Identifies Potential for Anticancer Drugs in Solanum Nigrum Fruits
May 5th 2023A recent study analyzed the composition and metabolism of steroidal alkaloids in Solanum nigrum fruits of different maturities and identified steroidal glycoalkaloids and steroidal alkaloids, providing a foundation for further research on biosynthesis and discovery of new steroidal alkaloid anticancer drugs.
Proteotypic Peptides of Hairs Can Be Used for Species Identification Using Mass Spectrometry
May 5th 2023A new published study introduces a simple and fast way to differentiate between animal species based on their hair. The in-sample digestion method coupled with mass spectrometry analysis was successfully tested on multiple species.
New SBSE–HPLC-DAD Method Proposed to Analyze Trace PCBs in Environmental Waters
May 3rd 2023Trace amounts of polychlorinated biphenyls (PCBs) in a river and lake in China were detected using a custom coating for stir bar sorptive extraction (SBSE) followed by high performance liquid chromatography with diode array detection (HPLC-DAD).
New Extraction Approach Combined with HPLC-UV to Monitor Chloramphenicol in Milk and Chicken
May 2nd 2023Researchers have developed a new approach to extract chloramphenicol (CAP) from milk and chicken samples using magnetic nanofluid-based deep eutectic solvents (DES), which was combined with high performance liquid chromatography-ultraviolet (HPLC-UV) analysis. The method was found to be low-cost, green, efficient, and effective in detecting even trace amounts of CAP.
Magnetic Solid-Phase Extraction (MSPE) with HPLC Method Developed for NSAID Analysis
May 2nd 2023Scientists have developed a magnetic ionic liquid hypercrosslinked polymer composite for use in magnetic solid-phase extraction (MSPE) of non-steroidal anti-inflammatory drugs (NSAIDs), which was coupled with high-performance liquid chromatography (HPLC) for the detection of trace amounts of NSAIDs in water and urine samples.
Wuhan University Researchers Develop New Method for Detecting Pyrethroid Pesticides in Tobacco
May 2nd 2023Researchers have developed a new method for detecting pyrethroid pesticide residues in tobacco using Schiff base networks (SNWs) coated stir bar sorptive extraction (SBSE) coupled with high performance liquid chromatography-ultraviolet detection (HPLC-UV), which exhibited high extraction efficiency and good mechanical stability even when reused more than 50 times.
New Method Developed to Map Cellulose Ether Monomer Composition
May 2nd 2023A new RPLC–MS method can map the substitution degree and composition of β-glucose monomers of cellulose ethers (CEs), providing detailed compositional distributions and constitutional isomer distributions, thereby identifying compositional variation between bio-stable and non-bio-stable CEs and unexpected methylations in EHEC samples.
When van Deemter Goes Upside Down in Chiral Chromatography
May 2nd 2023The occurrence of convex-upward van Deemter curves is rare but not unusual in chiral liquid chromatography. In this work, this behaviour, experimentally observed for the more retained enantiomer of a chiral sulfoxide on a polysaccharide-based CSP, is explained.
Using HPLC–MS and GC–MS for Improving Speed and Accuracy of Organosulfur Compound Detection
May 2nd 2023High performance liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry, along with numerous extraction methods, are helping to find organosulfur compounds in food more easily, providing researchers better information about the health benefits of these substances.
Exploring Biopharmaceutical Analysis with Compact Capillary Liquid Chromatography Instrumentation
A recent trend in the design of LC instrumentation is the move towards miniaturized and portable systems.
An LC–MS/MS Method for the Evaluation of Intestinal Permeability in Blood Plasma
May 1st 2023A rapid and robust LC–MS/MS method for determining lactulose and rhamnose concentrations in blood plasma was used to determine intestinal permeability from blood plasma, which can help diagnose gastrointestinal diseases such as Crohn’s disease.
Analysis of PFAS in Locally Acquired Food Containers
May 1st 2023The combination of an untargeted approach using ultrahigh pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF) and a targeted approach using UHPLC–tandem mass spectrometry (MS/MS) are presented as an ideal method for detecting per- and polyfluroalkyl substances (PFAS) in fast-food packaging.
LCE and LCA: Suspect Screening of Lupin-Produced Phytotoxins in Environmental Samples
April 30th 2023Selective pressurized liquid extraction and multilayer solid‑phase extraction methods are described for high‑throughput plant, soil, and water sample preparations. Optimal analytical conditions are described for the improvement of detection sensitivities and coverage. A Source Supported Suspect Screening (4S) approach is described; phytotoxins detected in the source plant were used to improve the identification of phytotoxins in soil and water.
Ion Chromatography Helps Researchers Identify Forest Fire Emissions in Rainfall Samples
April 28th 2023Researchers have shown the effectiveness of ion chromatography (IC) in identifying markers of forest fire emissions in rainfall samples, providing valuable insights into the signature of forest fire emissions and aiding in the development of models to predict and control air pollution resulting from these events.
New Nickel Oxide Stationary Phase for Improved HILIC Separation
April 27th 2023A new study has reported the preparation, characterization, and chromatographic evaluation of a nickel oxide deposited silica stationary phase in HILIC, which exhibited multiple retention mechanisms and enhanced chromatographic selectivity for analytes.