Application Notes: Sample Prep
Extraction of Acids, Neutrals, and Bases from Plasma
Strata-X PRO was chosen to extract a panel of acids, neutrals, and bases from plasma. This simple method eliminates time-consuming method development and recovery for extremely polar analytes.
Barbiturates from Serum Using Strata-X PRO Solid-Phase Extraction
Using Strata-X PRO to extract barbiturates from serum saves time by reducing the method to 3 quick and easy steps. In addition, the matrix is more effectively clean-up vs protein precipitation.
Strata-X PRO Solid-Phase Extraction Product Guide
Strata-X PRO consists of a new type of polymeric SPE sorbent combined with matrix removal technology to revolutionize sample extractions and matrix clean-up by eliminates the conditioning and equilibration steps.
A Faster SPE Method For Pain Relievers from Plasma Using Strata-X PRO
This application displays that for a range of pain relievers, an easy 3-Step SPE method can be implemented and produce high recoveries.
Two-Step Method for the Clean-Up of Veterinary Drugs in Milk
When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.
A Practical Guide for Small and Large Biomolecule Sample Preparation
In this webinar, learn how to achieve cleaner, more concentrated, and targeted sample preparation methods to help with downstream analysis for both analytical and biopharmaceutical labs.
High Recovery of Peptides Using Strata-X PRO Solid-Phase Extraction
For this peptide application, two different types of polymeric SPE (WCX and SAX) were tested in parallel with Strata-X PRO SPE and compared in regards to recovery and % variation.
Nanomedicine, well-characterized – how FFF-MALS provides detailed and quantitative analysis of size, structure, concentration and encapsulation
• FFF–MALS offers deep and unbiased particle characterization. • Regulatory bodies view FFF–MALS as essential for various nanomedicines.
Enhanced Aroma Profiling of Vodka
This study shows the advantages of automated immersive sorptive extraction for the GC–MS analysis of a wide range of aroma compounds in vodka.
Tackle Method 625.1 with Superior Evaporation
See the advantage in optimizing your solvent evaporation for maximum accuracy and precision to comply with U.S. EPA Method 625.1
Thermal-Desorption-GC/MS of Odors and Emissions
Aroma compounds in scented wax candles as well as aroma and odor emissions were determined by GC/MS after direct thermal extraction and air sampling with sorbent tubes.
Easy Method Development for Bioanalytical Therapeutic Peptides
Implementing a peptide screening SPE plate determines the appropriate choice for a wide range of chemically diverse peptides.
Solid-Phase Extraction Method to Reduce Surfactant Interference
The optimized dual solid phase extraction (SPE) method was developed to significantly reduce the surfactant background from formulated drug products.
Quantitation and Clean-Up of Neutral and Sialylated Glycans
A HILIC solid phase extraction (SPE) and LC method that results in sensitive, effective, and a time savings for the clean-up of N-Glycans.
Fast Determination of Ibuprofen in Human Plasma
A fast analytical method including both sample preparation and LC–ƒMS/MS analysis of ibuprofen in human plasma.
Chiral LC–MS/MS Analysis of Amlodipine Enantiomers in Plasma
The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.
PFAS and GenX from Water by SPE and LC–MS/MS
GenX, along with 24 other PFASs, are analyzed simultaneously to achieve sub-ppt reporting limits.
Determination of Sterols in Olive Oil
A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.
Analysis of Opiates from Urine Using Large Reservoir Cartridge SPE
SPE is used in combination with LC–MS/MS to analyze a panel of opiates from a urine sample.