Application Notes: Sample Prep
Zebron ZB-PAH-EU and ZB-PAH-CT GC Columns Guide
Achieving up to 70% faster GC PAH analysis. The Zebron ZB-PAH-EU and ZB-PAH-CT enable targeted selectivity for PAHs in food, the environment, electronics, and fuel.
Faster Analysis of 18 Phthalates by GC-MS using Zebron™ ZB-PAH-CT GC Column
In this application we learn how ZB-PAH-CT provides a faster Phthalates analysis comapred to other GC column
Reproducible Dioxin Analysis of Fly Ash and Soil Samples Using Zebron™ ZB-Dioxin GC Columns
In this application we looked at the improved Dioxin analysis in Enviro matrix
Better Separations for PCDD/PCDF with Zebron Columns
In this application, we look at the improved separation and run time for PCDD and PCDF using Zebron ZB-Dioxin GC column.
Robust Analysis of Dioxins in Fish Oil Samples by GC-MS/MS on a Zebron™ ZB-Dioxin GC Column
This study has demonstrated that ZB-Dioxin GC columns provide improved resolution of critical pairs of dioxin in food matrix
Zebron ZB-Dioxin GC Column Guide
Zebron ZB-Dioxin columns analyze dioxins and furans in food matrices. This GC innovation is a proven single GC dioxin solution that tests productivity and throughput.
Zebron PLUS GC Inlet Liners v2
Inert GC inlet liners for sample protection are easy to install. Touchless packaging allows protection from cuts, reducing contamination in the installation process.
Zebron Gas Management Guide v2
Zebron gas management filters and Traps removes contaminants from mobile phase gases to reduce column bleed and protects sensitive GC detectors from damage.
Determination of Volatile Organic Compounds in Environmental Samples as per HJ639 using Zebron™ ZB-624PLUS™ GC Column
In this application, we learn how ZB-624PLUS provides optimal separation of over 60 VOCs within 27 minutes analysis time.
Peptide Fractionation Simplified
Increased proteomic depth: A simple, fast and reproducible peptide fractionation add-on kit to the PreOmics iST kit family for sample preparation.
How to Avoid Contamination in Pipetting EU
Preventing cross contamination during pipetting is vital for accurate and reliable results. In order to avoid it you need to be aware of the potential sources.
Avoiding Depurination During Trityl-on Purification
This technical note explores a new trityl-on procedure that minimizes the risk of depurination.
Clarity OTX Application Guide
Extraction of oligo therapeutics from biological samples for LC–MS bioanalysis
Extraction of 2’-MOE Phosphorothioate from Plasma Using Clarity OTX
Using the Clarity OTX extraction protocol vendor recommendations, we have demonstrated its use to develop a method for the extraction of therapeutic oligos from plasma.
RNA Sample Preparation and High Throughput Purification for TBDMS and TOM Chemistries
This technical note discusses 2' cleavage and RNA sample preparation prior to trityl-on Clarity QSP cartridge or high-throughput purification.
Automated Method Development of Oligonucleotide in Tissues Using Clarity OTX 96-Well Plate and High-Resolution Mass Spectrometry
As synthetic oligonucleotide therapeutics traverse the drug-development path, there is an increasing need for TK and PK/PD studies in drug discovery and development.
FAQs for the Isolation and Purification of Synthetic Oligonucleotides
Common frequently asked question for oligonucleotides. This includes questions about characterization to purification and from sample preparation to LC separation.
Extraction and LC/MS Analysis of Oligonucleotide Therapeutics from Biological Matrices Using Clarity® OTX™ SPE and Clarity Oligo-MS™ HPLC/UHPLC Columns
This technical note discusses a simple, yet quick and effective solution for isolating and analyzing therapeutic oligonucleotides using Clarity OTX, an extraction kit.
Clarity Biosolutions for Synthetic DNA/RNA Guide
Advance your oligonucleotide work, from sample preparation to analysis and purification
Extraction of 2’-MOE Phosphorothioate from Tissue Using Clarity OTX Solid Phase Extraction (SPE)
To ensure recovery and reproducibility for oligo extraction from tissue, it is imperative that an effective sample pretreatment strategy is used.
Comparing Performance of High-Throughput, Trityl-on RNA/DNA Purification Products
Clarity QSP provides an alternative trityl-on approach for separating truncated sequences and synthetic contaminants from the protected full-length sequence.
Analysis of 26 Natural and Synthetic Opioids in Blood and Urine
UCT offers a simple yet effective procedure to extract and monitor an extensive panel of opioids in blood and urine using solid-phase extraction (SPE) combined with UHPLCMS/MS.
Extraction of Amphetamines from biologicals using Clean Screen DAU
This application note describes a simple and robust solid-phase extraction (SPE) procedure for amphetamines in blood, plasma/serum, urine, and tissue samples.
Summary of FDA Method C-010.01: Perfluoroalkyl and Polyfluoroalkyl Substances in Food
This application note summarizes a validated procedure developed by the US Food and Drug Administration (FDA) for the measurement of 16 PFASs in food using a QuEChERS sample preparation approach.
Monitoring Acrylamide in Real-Time During Food Production Using SIFT-MS
Known carcinogen, acrylamide is formed during food production processes such as roasting. This study details the use of SIFT–MS to monitor for this VOC in real time.
Cannabis Testing: Are We Missing Low-Abundance Contaminants by Skipping Sample Preparation?
Fully Automated Solution for Nitrosamines Analysis
This application note provides an optimised and validated fully automated sample preparation and LC–MS/MS analysis solution for seven target nitrosamines in two classes of drug substance.
Extraction of Mitragynine and 7-Hydroxymitragynine from Blood and Urine
A quick, easy, effective procedure to identify and quantitate Kratom analytes in blood and urine using Clean Screen® XCEL I SPE cartridges and a Selectra® C18 UHPLC column.
Barbiturates, Benzodiazepines, and THC in Oral Fluid
UCT’s polymeric Styre Screen® HLD sorbent analyzes a wide range of neutral drugs in oral fluid.
Extraction of Amphetamines from Biologicals
This application note describes a simple and robust solid-phase extraction (SPE) procedure for amphetamines in blood, plasma, serum, urine, and tissue samples.