Column: LC Troubleshooting

Jul 01, 2017
LCGC North America
We consider some of the details associated with preparing a column for storage, with an eye toward choices that will pay dividends in future use.
Jun 01, 2017
LCGC North America
How much of a change can you make to a USP method without revalidating the method?
May 01, 2017
LCGC North America
To change selectivity in LC, which variable should you choose?
Apr 01, 2017
LCGC North America
Learn how to find the “sweet spot” in terms of retention for a liquid chromatography separation and how to estimate how much a change in mobile-phase percent organic will affect retention.
Mar 01, 2017
LCGC North America
Here’s how to estimate the effects of changes in column length and particle diameter without conducting experiments in the laboratory.
Feb 01, 2017
LCGC North America
Proper filtering is important to protect LC system components and deliver high quality analytical results. In some cases, however, it makes sense to deviate from best practices.
Jan 01, 2017
LCGC North America
Mobile-phase pH is a powerful tool, but must be controlled properly.
Dec 01, 2016
LCGC North America
This case study shows how to troubleshoot an LC method problem.
Nov 01, 2016
LCGC North America
What could cause a peak to be eluted before the column dead time?
Oct 01, 2016
LCGC North America
Interfering peaks or high baseline background can compromise the results of gradient LC separations.
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