Liquid Chromatography (LC/HPLC)

Jun 30, 2015
LCGC North America
Here, we concentrate on one particularly useful equation that allows us to make changes to an analytical system to improve throughput or efficiency, while retaining the selectivity of the original method.
Jun 30, 2015
LCGC North America
We consider the potential causes of peak distortion for the first two peaks in the chromatogram.
Jun 09, 2015
LCGC Europe
A question that keeps raising its head when working in a regulated laboratory is can chromatographers integrate peaks manually? If they can, when can they do it? Also if they can manually integrate, when should they not do it?
Jun 04, 2015
The Column
A selection of commonly asked questions about GPC/SEC from users.
May 31, 2015
LCGC North America
This work presents an on-line combination of a simple microgradient device for reversed-phase liquid chromatography (LC) and electrospray ionization (ESI) tandem mass spectrometry (MS-MS).
May 31, 2015
LCGC North America
Readers' questions regarding problems related to internal standard calibration of liquid chromatography methods are addressed.
May 31, 2015
LCGC North America
The use of superficially porous particles in the manufacture of high performance liquid chromatography (HPLC) columns has become prominent in recent years. Over the course of the past decade most major manufacturers have built column lines around the technology.
May 31, 2015
LCGC North America
This installment provides an overview of modern practices of high-throughput purification to support small-molecule drug discovery.
Apr 09, 2015
The Column
Changes to the European Food Safety Authority (EFSA) regulations on food labelling, and the strengths and limitations of new and existing methods for the detection of allergens in food are discussed in this article.
Apr 08, 2015
The Column
A rapid and reliable high performance liquid chromatography–mass spectrometry (HPLC–MS) method to determine amino acids in beer is presented.