Liquid Chromatography (LC/HPLC)

Aug 10, 2015
The Column
Automated high-throughput dynamic light scattering (HT–DLS) can enable rapid and unattended assessment of sample purity in biopharmaceutical samples, maximizing the reliability and productivity of the candidate selection process. This article explains more.
Jul 01, 2015
LCGC North America
Here, we concentrate on one particularly useful equation that allows us to make changes to an analytical system to improve throughput or efficiency, while retaining the selectivity of the original method.
Jul 01, 2015
LCGC North America
We consider the potential causes of peak distortion for the first two peaks in the chromatogram.
Jun 05, 2015
The Column
A selection of commonly asked questions about GPC/SEC from users.
Jun 01, 2015
LCGC North America
This work presents an on-line combination of a simple microgradient device for reversed-phase liquid chromatography (LC) and electrospray ionization (ESI) tandem mass spectrometry (MS-MS).
Jun 01, 2015
LCGC North America
Readers' questions regarding problems related to internal standard calibration of liquid chromatography methods are addressed.
Jun 01, 2015
LCGC North America
The use of superficially porous particles in the manufacture of high performance liquid chromatography (HPLC) columns has become prominent in recent years. Over the course of the past decade most major manufacturers have built column lines around the technology.
Jun 01, 2015
LCGC North America
This installment provides an overview of modern practices of high-throughput purification to support small-molecule drug discovery.
Jun 01, 2015
LCGC Europe
A question that keeps raising its head when working in a regulated laboratory is can chromatographers integrate peaks manually? If they can, when can they do it? Also if they can manually integrate, when should they not do it?
Apr 10, 2015
The Column
Changes to the European Food Safety Authority (EFSA) regulations on food labelling, and the strengths and limitations of new and existing methods for the detection of allergens in food are discussed in this article.