Various extraction methods for the simultaneous determination of veterinary drugs in several matrices (milk, egg and honey) by ultra high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS–MS) are described. The following extraction techniques have been used: solvent extraction, solid-phase extraction (SPE) and modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe). The three proposed methods are validated and the advantages and disadvantages of them are outlined.

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Various extraction methods for the simultaneous determination of veterinary drugs in several matrices by UHPLC–MS–MS are described.

Multiclass Analysis of Veterinary Drugs in Complex Matrices by UHPLC–MS–MS

CHROMacademy — a cutting-edge e-learning programme — offers continuing professional development to the chromatography community. Tony Taylor spoke to The Column about the benefits this approach offers chromatographers.

CHROMacademy offers continuing professional development. Tony Taylor spoke to The Column about the benefits this approach offers chromatographers.

Climbing the Learning Curve

Headlines continue to warn consumers about the hidden dangers of toxic chemicals in domestic products, most importantly, children’s toys. Plasticizers often used to soften plastics, such as phthalates, have been in the news due to a recent study on the cumulative effects in young children of phthalates exposure from consumer products. Dr William Goodman, Chromatography Applications Manager and Dr Nicola Vosloo, European Market Development Leader, PerkinElmer, explain the importance of sensitive detection in phthalate testing during GC–MS analysis.

Explaining the importance of sensitive detection in phthalate testing during GC–MS analysis.

The Column-02-22-2010

Multiclass Analysis of Veterinary Drugs in Complex Matrices by UHPLC–MS–MS

Climbing the Learning Curve

Playing it Safe with Sensitive Phthalate Analysis