August 22nd 2024
A recent study analyzed nearly 100 CBD products to test the accuracy of advertised cannabinoid content.
The 26th Norwegian Symposium on Chromatography
March 29th 2024The 26th Norwegian Symposium on Chromatography was held 21–23 January 2024. The symposium has strong traditions in the Norwegian separation science community, serving as a forum for excellent scientific talks, networking, and social events.
THC Isomers in Cannabis: An EAS Interview with Brandy Young
November 17th 2023Brandy Young, PhD, an analytical chemist with more than 15 years of experience, entered the cannabis industry in response to a recognized need for laboratory testing, aligning her expertise with the emerging demand in New York's active medical and adult-use cannabis programs. Here, she shares some background information on her Eastern Analytical Symposium (EAS) talk, which delves into the characterization of tetrahydrocannabinol (THC) isomers in cannabis products.
Purification and Isolation of Cannabinoids: Current Challenges and Perspectives
The current challenges and future perspectives of the purification of cannabinoids from cannabis extracts are presented in this review article.
The LCGC Blog: Analyzing Trends of the Cannabis Testing Market
November 1st 2021The phenomenon known as the “green rush” outpaces all significant analytical market areas. Given all this excitement, it is worth stepping back to examine the overarching trends and nuances of the cannabis testing environment and offer some opinions about the key players and disruptive technologies gaining traction throughout this burgeoning marketplace.
Determination of Seventeen Phytocannabinoids in Various Matrices by UHPLC–HRMS/MS
January 1st 2020A simple ultrahigh-performance liquid chromatography high resolution tandem mass spectrometry (UHPLC−HRMS/MS) method to determine seventeen phytocannabinoids was developed and validated for Cannabis plants, resins and their extracts, and oils. The analysis was challenging because of the complexity of matrices, the large differences in the concentration of phytocannabinoids and their pattern in various cultivars, and the structural similarity of these analytes.
Determination of Cannabidiol and Additional Cannabinoid Content in Hemp Tea
September 10th 2019Quantification of cannabinoids is essential for the accurate labelling of hemp products, both for quality control and for establishing legality with regards to d9-tetrahydrocannabinol (THC) content. For this article, the cannabinoid content of several cannabidiol (CBD)-rich hemp tea samples was determined and was found to often deviate from the content stated on the packaging. Just like the cannabis flower, hemp tea can be analyzed easily and effectively for its cannabinoid content using high performance liquid chromatography (HPLC). The HPLC–UV assay of choice provided good linearity, low limits of detection (LODs), and high precision of retention time and peak area for the 11 cannabinoids under investigation.
Advancing Chromatography Methods for Cannabis Analysis
August 13th 2018The cannabis industry has been taking a hard look at the science behind their products and the various contaminants that can inadvertently be added to consumer goods. As testing laboratories begin to implement new state-mandated regulations and other consensus methods for best practices, there is a need to review the analytical instruments and methods that can deliver the most accurate results in a timely fashion. Anthony Macherone, senior scientist at Agilent Technologies and visiting scientist at the Johns Hopkins University School of Medicine, recently spoke to us about his research in this area and the chromatographic techniques he has found to be most effective for profiling cannabinoids and terpenes, detecting pesticides, and residual solvents testing.
The LCGC Blog: Pesticide Analysis in Cannabis: Choosing the Right Technique
October 30th 2017The presence of capable students and researchers, each with a technical niche to offer, prepares us for future opportunities. On top of that structure, we also aim to maintain this mindset for our instrument selection before beginning projects. The installment of core labs at UT Arlington (www.uta.edu/sirt), making a wide range of instruments available to all research groups, has allowed our students to brainstorm about which instrument is the most appropriate for a specific analysis rather than how to make a measurement work with a given instrument.
Determination of Cannabinoid Content and Pesticide Residues in Cannabis Edibles and Beverages
October 1st 2017As a result of the rapid growth of the cannabis industry, many testing laboratories are looking for efficient, reliable, and cost-effective analytical methods to analyze chemical residues, such as pesticides, mycotoxins, solvent residues, terpenes, and heavy metals, as well as cannabinoid concentration in cannabis-infused edibles and beverages. In this article, QuEChERS (quick, easy, cheap, effective, rugged, and safe), a sample preparation technique widely adopted in the food testing industry, is introduced to the discipline of forensic testing as a viable method for the extraction of pesticides and cannabinoids in various complex sample matrices. The claimed amounts of cannabinoids versus the actual amounts are compared, as well as the pesticide residue levels in edible and beverage samples.