LC–MS

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Multi-Step Preparative LC–MS Workflow for Peptide Purification
Multi-Step Preparative LC–MS Workflow for Peptide Purification

March 21st 2025

This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.

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Determining N-Nitrosamines in Pharmaceutical Preparations Using LC–MS/MS

March 20th 2025

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Characterizing Oligosaccharides in Breast Milk with Liquid Chromatography

March 20th 2025

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Testing Smart Proteolytic Samplers for Protein Quantification

March 19th 2025

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LC-MS/MS Approach for PFAS Detection in Food Contact Materials

March 18th 2025

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