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© 2023 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2023 MJH Life Sciences™ and Chromatography Online. All rights reserved.
September 19, 2023
This review of pharmaceutical analysis in the last three years includes three categories of chiral liquid chromatography stationary phases: saccharides, macrocyclic substances, and porous organic materials.
September 14, 2023
Researchers from Hebei University in China have developed and characterized three novel peptide chiral stationary phases (CSPs) for enantiomeric separation, demonstrating their potential in high performance liquid chromatography (HPLC).
August 17, 2023
A recent review article discussed advances in liquid chromatography (LC) enantioseparations.
August 11, 2023
Since similar chiral recognition mechanisms were observed for benzoin (B) and methyl mandelate (MM), a three-site enantioselectivity model was proposed to interpret the data being sought by researchers.
August 01, 2023
What can chiral capillary GC do for you? The answer lies in what analysis one is attempting to accomplish. Here, we discuss the utility of chiral capillary GC and where the technique is most valuable, focusing on three application areas in particular.
July 10, 2023
Although closantel (CLO) is well-regarded as a curative antiparasitic drug, even low doses have been found to cause serious side effects in the human retina and central nervous system.
Researchers have synthesized a chiral metal-organic framework (MOF) called L-histidine-zeolitic imidazolate framework-67 (L-His-ZIF-67) for enantioseparation of drugs in capillary electrochromatography. The chiral MOF demonstrated excellent separation efficiency for five chiral drugs, offering promising possibilities for pharmaceutical analysis and quality control.
June 27, 2023
Researchers have discovered that the combined use of deep eutectic solvents (DESs) and amino acid-based ionic liquids (AAILs) with cyclodextrin-based chiral selectors can significantly enhance the chiral separation of amphetamine derivatives.
June 20, 2023
A talk by Alberto Cavazzini of the University of Ferrara at HPLC 2023 focused on various types of chiral stationary phases (CSP) in efforts to improve efficiency.
May 17, 2023
Mono-type, blending-type, coating-type, and bonding-type chromatographic packings based on chiral metal-organic frameworks (CMOFs) were analyzed regarding their effectiveness in enantioseparation.