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Patrick Lavery is an Editor for the MJH Life Sciences brands LCGC and Spectroscopy, and their respective websites, 

. He previously spent nearly a decade as a news anchor, reporter, and producer at New Jersey 101.5 FM.

Articles

This review of pharmaceutical analysis in the last three years includes three categories of chiral liquid chromatography stationary phases: saccharides, macrocyclic substances, and porous organic materials.

Recent Chiral Stationary Phase Advancements in HPLC Analysis

Events

Researchers from Hebei University in China have developed and characterized three novel peptide chiral stationary phases (CSPs) for enantiomeric separation, demonstrating their potential in high performance liquid chromatography (HPLC).

Newly Devised Peptide Chiral Stationary Phases Evaluated for Enantioselectivity in HPLC Applications

A recent review article discussed advances in liquid chromatography (LC) enantioseparations.

Separation of Chiral Enantiomers in LC Enantioseparations

Since similar chiral recognition mechanisms were observed for benzoin (B) and methyl mandelate (MM), a three-site enantioselectivity model was proposed to interpret the data being sought by researchers.

Enantioselectivity in LC Evaluated by Variations in Modifiers and Modifier Concentration

What can chiral capillary GC do for you? The answer lies in what analysis one is attempting to accomplish. Here, we discuss the utility of chiral capillary GC and where the technique is most valuable, focusing on three application areas in particular.

Chiral Capillary Gas Chromatography: A Highly Selective Analytical Tool

Although closantel (CLO) is well-regarded as a curative antiparasitic drug, even low doses have been found to cause serious side effects in the human retina and central nervous system.

LC–MS/MS with Postcolumn Ammonia Infusion Determines Ultratrace Enantiomers of Closantel in Bacteria

Researchers have synthesized a chiral metal-organic framework (MOF) called L-histidine-zeolitic imidazolate framework-67 (L-His-ZIF-67) for enantioseparation of drugs in capillary electrochromatography. The chiral MOF demonstrated excellent separation efficiency for five chiral drugs, offering promising possibilities for pharmaceutical analysis and quality control.

Researchers Develop Chiral Metal-Organic Framework for Enantioseparation of Drugs by Capillary Electrochromatography

Researchers have discovered that the combined use of deep eutectic solvents (DESs) and amino acid-based ionic liquids (AAILs) with cyclodextrin-based chiral selectors can significantly enhance the chiral separation of amphetamine derivatives. 

Synergistic Enhancement of Chiral Discrimination in Capillary Electrophoresis Using Deep Eutectic Solvents and Amino Acid-Based Ionic Liquids

A talk by Alberto Cavazzini of the University of Ferrara at HPLC 2023 focused on various types of chiral stationary phases (CSP) in efforts to improve efficiency.

New Insights into Chiral Chromatography: Exploring Efficient Separation Methods and Enantioselectivity Assessment

Mono-type, blending-type, coating-type, and bonding-type chromatographic packings based on chiral metal-organic frameworks (CMOFs) were analyzed regarding their effectiveness in enantioseparation.

Chiral Chromatography | Topics