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© 2021 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2021 MJH Life Sciences™ and Chromatography Online. All rights reserved.
August 18, 2021
AAV characterization and stability screening are achieved with multi-angle light scattering coupled to separation methods and high-throughput dynamic light scattering.
June 01, 2021
Learn how AAVs are characterized for critical quality attributes and stability by multi-angle and dynamic light scattering.
March 26, 2021
We investigated the purification and size-exclusion chromatography and light scattering analysis of virus-like particles.
This application note demonstrates the separation of IgG monomers and its aggregates, antibody metabolites, and other proteins.
LC–MS analysis of various low molecular weight cationic compounds were demonstrated using gradient formic acid and acetonitrile eluents.
Oligonucleotides were then analyzed using liquid chromatography with ultraviolet and mass spectrometry with a polymer-based diol column.
February 11, 2021
This note describes how SEC-MALS-UV-RI analysis quantifies multiple critical quality attributes of AAV viral vectors, including concentration/titer, aggregation and empty:full ratio.
October 09, 2020
Combining the benefits of the ACQUITY APC System with the ACQUITY UPLC Refractive Index (RI) Detector and the ACQUITY QDa Mass Detector yields laboratory efficiencies.
The selection of appropriate column chemistries to separate eighteen polymer additives are routinely monitored in extractables and leachables (E&L) workflows.
A flexible analytical system was used in conjunction with a well-defined informatics workflow to elucidate degradation markers in Li-Ion battery electrolytes.