Application Notes

Articles

Combining the benefits of the ACQUITY APC System with the ACQUITY UPLC Refractive Index (RI) Detector and the ACQUITY QDa Mass Detector yields laboratory efficiencies.

Characterization of Polymer Additives

The selection of appropriate column chemistries to separate eighteen polymer additives are routinely monitored in extractables and leachables (E&L) workflows. 

Column Screening for UPLC Separation 

A flexible analytical system was used in conjunction with a well-defined informatics workflow to elucidate degradation markers in Li-Ion battery electrolytes.

Aiding Lithium Ion Battery Electrolyte Design

Combining the APC System with WinGPC UniChrom™ software allows researchers to increase the peak capacity of their research.

Two-Dimensional Liquid Chromatography for Polymer Applications

Collaborative efforts at Virginia Tech University drive better materials through polymer innovation and additive manufacturing.

Accelerating Additive Manufacturing Breakthroughs

How UHP‑SEC‑MALS analysis using a UHPLC compatible multi-angle light scattering detector can be applied to determine absolute molecular weight of recombinant proteins.

SEC-MALS Analysis of Biotherapeutics

Learn how light scattering characterizes multiple biophysical attributes of different vaccine modalities in support of discovery, development, manufacture, and QC.
 


Characterizing Vaccines with Light Scattering

Comprehensive physicochemical characterization of biopolymers is accomplished by adding multi-angle light scattering and differential viscometry to standard SEC.


Analysis of Hyaluronic Acid by SEC-MALS-IV

Branching impacts polymer properties such as rheology and stiffness. This note explains the analysis of branching ratio versus molar mass, accomplished by SEC-MALS(-IV).

Polymer Branching Analysis by SEC-MALS-IV

How do bioinert and biocompatible liquid chromatography (LC) systems and columns improve separations of biomolecules? How do I know when these systems are required for my separation?

Application Notes: Size-Exclusion Chromatography (SEC)