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© 2022 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2022 MJH Life Sciences™ and Chromatography Online. All rights reserved.
December 01, 2022
The methodologies demonstrated here open the way to fully compliant at-line monitoring of monoclonal antibody quality attributes.
November 01, 2022
Pepsin digestion and guanidine hydrochloride post-digestion can improve sequence coverage in antibody peptide mapping compared with trypsin digestion.
October 01, 2022
The method presented here, which uses a novel needle trap device (NTD)
with sol-gel PEG-coated fibers in conjunction with GC, is a simple, inexpensive, and accurate tool for the analysis of trace levels of PCBs in water samples.
September 01, 2022
This article presents a new hydrophilic SAX hybrid monolithic column prepared by in‑capillary coating 5 μm bare silica particles with functional organic polymers. After preparation conditions were investigated and selected, the resulting column was characterized in detail.
Online 2D-LC is a powerful—and accessible—tool for analyzing pharmaceutical and biopharmaceutical samples, in both R&D and QC. It’s now easier than ever to develop 2D-LC methods, and they can be run in a fully automated manner.
August 01, 2022
Headspace GC reveals that sonication can degrade common organic solvents.
July 01, 2022
Acoustic ejection mass spectrometry (AEMS) has recently emerged as the premier ultrahigh-throughput mass spectrometric methodology for drug discovery and related fields.
June 01, 2022
Lipids in SFC are mainly separated according to their lipid classes, which simplifies quantification with standards. In this study, SFC coupled with drift time IM‑QTOF-MS was used to characterize the HepG2 lipidome.
May 01, 2022
A generalized approach using DoE is presented for the optimization of DHS extraction parameters.
April 14, 2022
Supplementary data to Dias et al., LCGC Europe 35(5), 163–170 (2022).