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Characterizing lipid nanoparticles (LNPs) is a developing delivery modality in biotherapeutic analysis. We address some of the current challenges and opportunities in this field, including an examination of the most common 
tools used to characterize LNPs.

Analysis of Lipid Nanoparticles

Articles

Researchers in Iran utilize graphene oxide aerogels to significantly improve the extraction and analysis of risperidone from plasma samples, offering enhanced accuracy and efficiency in pharmaceutical analysis.

Enhancing Risperidone Analysis: Graphene Oxide Aerogels Facilitate Efficient Extraction from Plasma Samples for HPLC-UV Analysis

A new publication introduces a groundbreaking automated system for high-throughput mass spectrometry analysis, reshaping the future of biotherapeutic characterization.

Revolutionizing Biotherapeutic Analysis: The Automated Future of Mass Spectrometry

A recent study has introduced comprehensive quality control procedures for large-scale plasma proteomics analyses. The research provides valuable insights into optimizing performance, enhancing reproducibility, and ensuring quantitative accuracy in proteomics investigations.

New Procedures Enhance Quality Control for Large-Scale Plasma Proteomics Analyses

A novel analytical method combines charge inversion ion-ion reactions with ion mobility–mass spectrometry to enhance the separation and characterization of oligosaccharides.

New Method Enables Enhanced Separation of Oligosaccharides Using Ion Mobility-Mass Spectrometry (IM–MS)

A new tandem mass spectrometry technique has been developed for the rapid determination of complex lipid A structures, including novel variations from arctic bacterioplankton. This study enhances our understanding of bacterial adaptations and paves the way for the development of targeted therapies and antimicrobial agents.

New Technique Reveals Hidden Structures of Lipid A with Multiple Glycosylation Sites

A cutting-edge technique combining droplet microfluidics and mass spectrometry revolutionizes monoclonal antibody screening, enabling rapid and high-throughput analysis while setting a new standard for efficient clone selection in biopharmaceutical development.

Revolutionizing Clone Selection: Droplet Microfluidics and Mass Spectrometry for High-Throughput Monoclonal Antibody Screening

Automation and high-throughput MALDI mass spectrometry revolutionize peptide metabolic stability screening, allowing for rapid analysis of a large number of samples and minimizing solvent waste.

Automation and High-Throughput MALDI-Mass Spectrometry Revolutionize Peptide Metabolic Stability Screening

A team of researchers have created an innovative analytical platform combining asymmetrical flow field-flow fractionation (AF4) with native mass spectrometry (nMS) to characterize non-covalent protein complexes, providing valuable insights into their stability and higher-order structures.

Characterizing Non-covalent Protein Complexes Using Asymmetrical Flow Field-Flow Fractionation On-Line Coupled to Native Mass Spectrometry

Researchers have developed a novel liquid chromatography–mass spectrometry method for analyzing sialic acid linkage in N-linked glycopeptides, offering insights into glycosylation patterns.

Biopharmaceuticals and Protein Analysis | Topics