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Researchers achieve a breakthrough in countercurrent chromatography, successfully separating three types of sanshools from Zanthoxylum bungeanum oleoresin, paving the way for enhanced purification and isolation of valuable compounds.

New Development in Countercurrent Chromatography: Efficient Separation of Sanshools from Zanthoxylum bungeanum Oleoresin

A new study introduces a comprehensive two-dimensional liquid chromatography coupled with tandem mass spectrometry (2D-LC–MS/MS) method for the analysis of 112 pesticides in corn-based products. The method exhibits high precision, lower limit of quantification values, and successful detection of trace levels of pesticides in real samples, offering promise for the analysis of complex matrices.

New Analytical Method Enables Multi-Class Analysis of Pesticides in Corn Products

Innovative gas chromatography (GC) study combines computer vision and chromatographic fingerprinting to uncover diagnostic signatures in food volatilome.

Augmented Visualization and Gas Chromatographic Fingerprinting Unveil Hidden Clues in Food Volatilome

A recent study analyzed the composition and metabolism of steroidal alkaloids in Solanum nigrum fruits of different maturities and identified steroidal glycoalkaloids and steroidal alkaloids, providing a foundation for further research on biosynthesis and discovery of new steroidal alkaloid anticancer drugs.

New Study Identifies Potential for Anticancer Drugs in Solanum Nigrum Fruits

A new published study introduces a simple and fast way to differentiate between animal species based on their hair. The in-sample digestion method coupled with mass spectrometry analysis was successfully tested on multiple species.

Proteotypic Peptides of Hairs Can Be Used for Species Identification Using Mass Spectrometry

A new approach for identifying isomeric and isobaric metabolites has been developed using liquid chromatography (LC) with high-resolution ion mobility spectrometry (IMS) and cryogenic infrared (IR) spectroscopy, allowing for faster, more accurate, and cost-effective metabolomics workflows.

New Approach for the Identification of Metabolites Using LC with Ion Mobility and Cryogenic Spectroscopy

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From Screening to Confirmation: A Comprehensive Food Safety Analysis from Initial DIA Screening to Automatic Reinjection for Suspect Confirmation

 is a postdoctoral researcher in analytical chemistry at the University of Messina.

 is an assistant professor of food chemistry at the University of Messina.

 is a senior scientist in the Analytical Research & Development team at MilliporeSigma.

 is a senior scientist in HPLC Analytical Research and Development at MilliporeSigma.

 is an associate professor of analytical chemistry at the University of Messina.


 is a full professor of food chemistry at the University of Messina.


 is a full professor of analytical chemistry at the University of Messina, and a member of the EAB for LCGC Europe.

This article highlights an advantage of porous graphitic carbon columns, that is their resistance at high temperatures, for the analysis of parabens in foodstuffs.

Evaluation of PGC Stationary Phases Under High-Temperature LC Conditions for the Analysis of Parabens in Food Samples

Researchers have developed a new method for detecting pyrethroid pesticide residues in tobacco using Schiff base networks (SNWs) coated stir bar sorptive extraction (SBSE) coupled with high performance liquid chromatography-ultraviolet detection (HPLC-UV), which exhibited high extraction efficiency and good mechanical stability even when reused more than 50 times.

Wuhan University Researchers Develop New Method for Detecting Pyrethroid Pesticides in Tobacco

 is with the Center for Environmental Sciences & Engineering, Institute of the Environment, at the University of Connecticut, Storrs, Connecticut.

 is with the Center for Environmental Sciences & Engineering, Institute of the Environment, at the University of Connecticut, Storrs, Connecticut. Direct correspondence to: 

The combination of an untargeted approach using ultrahigh pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF) and a targeted approach using UHPLC–tandem mass spectrometry (MS/MS) are presented as an ideal method for detecting per- and polyfluroalkyl substances (PFAS) in fast-food packaging.

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