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 is a Ph.D. student in the Department of Food Analysis and Nutrition, University of Chemistry and Technology, Prague (Czech Republic). His main research interests are analysis of chlorinated paraffins and mineral oil hydrocarbons.

 is a master’s student in the Department of Food Analysis and Nutrition, UCT Prague. His research topic is on the analysis of chlorinated paraffins employing liquid chromatography‑based techniques.

 is a Ph.D. student at the Department of Food Analysis and Nutrition, UCT Prague. Her research is focused on the application of LC–HRMS in metabolomic and lipidomic studies.

Tomas Kourimsky is a Ph.D. student in the Department of Food Analysis and Nutrition, UCT Prague. His research is focused on the analysis of MCPD and its esters employing GC–MS/MS and SFC–HRMS.

 is a research assistant in the Department of Food Analysis and Nutrition, UCT Prague. His main research interests (but not limited to) are the application of (high resolution) mass spectrometry in the analysis of bioactive compounds and contaminants in food.

Jana Hajslova is a professor at UCT Prague. She is the head of ISO 17025/2018 accredited laboratory and also heads a research group concerned with separation science in the field of food/environmental analysis. She is the chair of a series of prestigious international symposia, Recent Advances in Food Analysis (RAFA, www.rafa2021.eu).

Jana Pulkrabova is a professor of Food Chemistry and Analysis and a Head of the Department of Food Analysis and Nutrition at UCT Prague. Her research group studies groups of organic pollutants in food, internal and external environment, and human biological monitoring.

Articles

This article presents SFC and UHPLC—both coupled with HRMS—methods for the analysis of short-, medium-, and long-chain CPs in fish oil-based dietary supplements.

Application of Liquid- and SFC Coupled with HRMS for the Analysis of Short-, Medium-, and Long-Chain Chlorinated Paraffins in Dietary Supplements

Kevin A. Schug is a Full Professor and Shimadzu Distinguished Professor of Analytical Chemistry in the Department of Chemistry & Biochemistry at The University of Texas (UT) at Arlington. He joined the faculty at UT Arlington in 2005 after completing a Ph.D. in Chemistry at Virginia Tech under the direction of Prof. Harold M. McNair and a post-doctoral fellowship at the University of Vienna under Prof. Wolfgang Lindner. Research in the Schug group spans fundamental and applied areas of separation science and mass spectrometry. Schug was named the LCGC Emerging Leader in Chromatography in 2009, and most recently has been named the 2012 American Chemical Society Division of Analytical Chemistry Young Investigator in Separation Science awardee.

We analytical chemists have a lot to gain by applying machine learning to our field—such as by using it to efficiently reach optimal conditions for challenging separations.

Working with Data Scientists to Improve Online Chemical Extraction and Analysis

An overview of modern approaches to small-molecule drug discovery.

Small-Molecule Drug Discovery: Processes, Perspectives, Candidate Selection, and Career Opportunities for Analytical Chemists

We are investigating fundamental relationships between the structures of molecules and their interaction with different materials, in the context of on-line supercritical fluid extraction–supercritical fluid chromatography (SFE–SFC).

The LCGC Blog: Working with Data Scientists to Improve On-line Chemical Extraction and Analysis

Lipids in SFC are mainly separated according to their lipid classes, which simplifies quantification with standards. In this study, SFC coupled with drift time IM‑QTOF-MS was used to characterize the HepG2 lipidome.

Supercritical Fluid Chromatography Coupled with Drift Time Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry as a Tool for Lipid Characterization of HepG2 Cells

James P. Grinias is an Associate Professor in the Department of Chemistry & Biochemistry at Rowan University in Glassboro, New Jersey, and the winner of the 2022 Emerging Leader in Chromatography Award, which is presented by LCGC magazine. 

Improving Chromatography for Analysis of Biological and Pharmaceutical Molecules: James Grinias, the 2022 winner of the Emerging Leader in Chromatography Award  

Barry L. Karger and James P. Grinias are the winners of the 15th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively, for 2022. Here, we review their achievements.


The 2022 Winners of the Lifetime Achievement and Emerging Leader in Chromatography Awards

LCGC Announces the 2021 Winners of the Lifetime Achievement and Emerging Leader in Chromatography Awards

The optimization of adjustable factors in electrospray ionization (ESI) by design of experiments (DoE) is presented. This approach allows a comprehensive and systematic optimization of all relevant factors for the ionization of compounds and increases the understanding about factor influences on the ionization efficiency. 

Design of Experiment Strategy for an Electrospray Ionization Optimization in Supercritical Fluid Chromatography–Mass Spectrometry Coupling

This review article discusses the novel separation and detection strategies that are considered promising in clinical metabolomics to enhance the metabolome coverage. It includes hydrophilic interaction chromatography (HILIC), supercritical fluid chromatography (SFC), multidimensional LC approaches, as well as ion-mobility mass spectrometry (IM-MS) and data-independent acquisition (DIA) analysis methods.

Supercritical Fluid Chromatography (SFC) | Topics