March 1st 2023
Increasing inclusivity and equity in chemistry will require a positive instructor mindset, as well as invention, exploration, and trials.
The 2023 LCGC Salary Survey: How Workers Are Navigating A Tough Economic Landscape
August 1st 2023The fallout from the Covid-19 global pandemic remains in progress in 2023. Because of the current ongoing global recession, we anticipated that many workers would be concerned about their current jobs and how to adjust to rising inflation. In this year’s LCGC Salary Survey, we sought to explore these topics.
Where Is Separation Science Heading?
August 1st 2022In honor of LCGC’s 40th year, we asked leading chromatographers to share their perspectives on current challenges and their visions for the future, looking at fundamentals of the techniques as well as the impact of analytical developments in important areas like medical research, pharmaceutical development, and environmental studies. Here’s what they said.
The Future of Instrumentation and Columns in Liquid Chromatography
August 1st 2022Although smaller advances have been made in the past decades, the question remains whether further extending operating pressure and decreasing particle size remains a feasible approach, or whether drastically novel approaches are required.
Liquid Chromatography Column Design and Dimensional Analysis of the van Deemter Equation
August 1st 2022The fundamental mechanisms of band broadening are usually introduced to students through the van Deemter equation. Dimensional analysis of this equation can give physical meaning to the equation coefficients and enhance our understanding relative to qualitative descriptions. This approach can also guide improvements to future liquid chromatography (LC) column designs.
New Perspectives on Comparative Analysis for Comprehensive Two-Dimensional Gas Chromatography
August 1st 2022This article provides an overview of the development and current status of comparative analysis for GC×GC–TOF-MS data and how key limitations can be overcome with a novel tile-based pairwise analysis method.
Let’s Get Small: Miniaturizing Separations for Single-Cell Analysis
August 1st 2022Further miniaturization of separations will greatly extend the reach of single-cell proteomics, metabolomics, and lipidomics, but key challenges in instrumentation, column technology, and ionization sources must be addressed.
Accelerating Sample Preparation for the Analysis of Complex Samples
August 1st 2022Given that sample preparation consumes over two thirds of analysis time, sample preparation becomes the bottleneck issue in analytical chemistry, resulting in the urgent necessity of developing accelerated sample preparation techniques.
Whither Gas Chromatography? New Tools ~ New Solutions
August 1st 2022We might well ask “Where is gas chromatography (GC) heading?” For many analysts, the answer may be just “more of the same,” reflecting that GC is mature and that most analysis tasks and sample types have been tried and tested. In this scenario, any changes to the basic method may be marginal—sample introduction, and maybe a new detector? But beneath this status quo is an undercurrent of passion, excitement, and power.
Recent Developments in HPLC and UHPLC: From Our Guest Editor
June 1st 2022In this issue, we feature fundamental and innovative efforts from within the walls of some the leading companies in the separation science industry. The theme was inspired by the continuous output of essential separation tools and the seemingly endless streams of pertinent information that these companies provide the scientific community.
The LCGC Blog: Whence the Next Generation of Macromolecular Separations Scientists?
March 30th 2022It is of paramount importance that companies develop their in-house macromolecular separations expertise, not only polymer manufacturing companies but also those employing macromolecules for any of a host of applications, from drug-delivery and tablet coatings to ink-jet printer formulations and food additives, to name but a few.