Topic

Articles

Increased diversity in the workplace brings broader perspectives and innovation. Yet many chemical industries, including separation science, lack the diversity that is representative of the population. To fix this problem, we must start at the beginning of the pipeline.

The LCGC Blog: Efforts to Increase Diversity and Equity in Introductory Chemistry

Laura Bush is a former managing editor of 

. She is currently the Editor-in-Chief of 

. 485 Route One South, Building F, First Floor, Iselin, NJ 08830, lbush@advanstar.com, tel. 732.346.3020

As we celebrate the 40th year of LCGC, we are thinking not about the past, but about the future.

From the Editor: Solving Tomorrow’s Challenges

In honor of LCGC’s 40th year, we asked leading chromatographers to share their perspectives on current challenges and their visions for the future, looking at fundamentals of the techniques as well as the impact of analytical developments in important areas like medical research, pharmaceutical development, and environmental studies. Here’s what they said.

Where Is Separation Science Heading?

The recruitment of young, talented entrepreneurs within academia and industry is needed to tackle many of the challenges that exist today and that will emerge tomorrow.

A Field Full of Opportunities: Transforming the Future of Separation Science

Small metabolic molecules often are chiral and can play important roles in regulating a variety of biological functions, occasionally providing information about the presence and progression of disease.

Analysis of D-Amino Acids: Relevance in Human Disease

Although smaller advances have been made in the past decades, the question remains whether further extending operating pressure and decreasing particle size remains a feasible approach, or whether drastically novel approaches are required.

The Future of Instrumentation and Columns in Liquid Chromatography

The fundamental mechanisms of band broadening are usually introduced to students through the van Deemter equation. Dimensional analysis of this equation can give physical meaning to the equation coefficients and enhance our understanding relative to qualitative descriptions. This approach can also guide improvements to future liquid chromatography (LC) column designs.

Liquid Chromatography Column Design and Dimensional Analysis of the van Deemter Equation

Kevin A. Schug is a Full Professor and Shimadzu Distinguished Professor of Analytical Chemistry in the Department of Chemistry & Biochemistry at The University of Texas (UT) at Arlington. He joined the faculty at UT Arlington in 2005 after completing a Ph.D. in Chemistry at Virginia Tech under the direction of Prof. Harold M. McNair and a post-doctoral fellowship at the University of Vienna under Prof. Wolfgang Lindner. Research in the Schug group spans fundamental and applied areas of separation science and mass spectrometry. Schug was named the LCGC Emerging Leader in Chromatography in 2009, and most recently has been named the 2012 American Chemical Society Division of Analytical Chemistry Young Investigator in Separation Science awardee.

The lack of proper method validation has important implications in blood alcohol concentration (BAC) determinations. We examine this issue, addressing the importance of gas chromatography (GC) for BAC determination, why certain validation procedures are important, and why accreditation bodies need to step up their game.

Accredited Forensics Laboratories Are Not Properly Validating and Controlling Their Blood Alcohol Determination Methods

Further miniaturization of separations will greatly extend the reach of single-cell proteomics, metabolomics, and lipidomics, but key challenges in instrumentation, column technology, and ionization sources must be addressed.

Let’s Get Small: Miniaturizing Separations for Single-Cell Analysis

Given that sample preparation consumes over two thirds of analysis time, sample preparation becomes the bottleneck issue in analytical chemistry, resulting in the urgent necessity of developing accelerated sample preparation techniques.

Trends | Topics