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Ed Ahearne combined automation, machine learning, and Bayesian optimization to speed up method development for siRNA medicines.

Data-independent acquisition (DIA) liquid chromatography-tandem mass spectrometry (LC–MS/MS) reveals shared and site-specific proteins across the thighbone.

Laura Righetti explains why quantification, not instrumentation, still keeps mass spectrometry imaging (MSI) out of routine food safety testing.

Large language models help chromatographers build LC pressure troubleshooting apps in hours.

Magnetic molecularly imprinted polymer extraction with liquid chromatography-high resolution mass spectrometry (LC–HRMS) finds patulin in store-bought juice.

Richard Bade and Malcolm McLeod explain to LCGC International how liquid chromatography-tandem mass spectrometry (LC-MS/MS) detects drug trends in wastewater.

In this fifth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor discusses how to overcome challenges with reversed-phase chromatography in drug analysis.

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) and microbiome data reveal kidney markers of diabetic disease.

Ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS) shows Maresin1 drops in heatstroke and may protect the heart.

Liquid chromatography–mass spectrometry (LC–MS) was used to determine if there is a link between artificial sweeteners and breast cancer.

Chiral gas chromatography–mass spectrometry (GC–MS) shows how heat and storage alter linalool in blueberry juice.

Anneli Kruve reports that toxicity predictions from MS2-derived molecular fingerprints outperform spectral-similarity methods in nontarget screening of food.

In this fourth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why buffers are most often used in Mobile Phase A in high-pressure liquid chromatography of pharmaceuticals.