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Size exclusion chromatography (SEC) plus precipitation improves extracellular vesicle (EV) purity from blood plasma.

Nitish Sharma and Piotr Alvarez compare reverse-phase separations of small molecules vs. peptides, from pI value and hydrophobicity to impurity profiles.

Meet the expert panel exploring the challenges involved in GLP-1 analysis in this LCGC International Peer Exchange®.

Ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) shows flonicamid residues in rice pose negligible dietary risk.

High-performance liquid chromatography-tandem mass spectroscopy (HPLC–MS/MS) chromatography reveals pyrrolizidine alkaloids (PA)/pyrrolizidine alkaloid N-oxides (PANO) toxin risks in 63 tea samples.

Advances in DNA/RNA chromatography columns led to stable, pure mRNA production, supporting the development of COVID-19 vaccines rapidly.

Steven Ray Wilson's AFFL LC–MS system runs thousands of injections per column, but he calls validation and standardization the field's real barrier.

Kinjal Bhatt and Ina Varfaj describe imposter syndrome fading through repeated exposure and conference talk rather than a single breakthrough moment.

Mass spectrometry can teach core chemistry concepts beyond technique training or product characterization, though adoption barriers remain.

Ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) tracks blood metabolite changes after repetitive transcranial magnetic stimulation (rTMS)-cognitive training therapy.

Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.

SFC Europe 2026 brings global experts to Basel for courses, scientific talks, workshops, and insights into greener separation technologies.

A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.