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A multinational research group developed and validated an in-house sample preparation procedure and liquid chromatography with tandem mass spectrometry (LC-MS/MS) method to monitor the suspected carcinogen acrylamide (AA) in 113 potato chip samples from Iranian brands during two periods: 2016-2017 and 2020-2021.

David S. Hage discusses the key trends and emerging topics in separation science and bioanalysis that are driving innovation in analytical chemistry and its applications to complex biological systems.

Researchers from the United Kingdom’s National Measurement Laboratory (NML) developed and evaluated a tailored mass spectrometry (MS)-based workflow for the detailed characterization and quantification of rAAV serotype 9 (rAAV9) capsid proteins.LCGC International spoke to Theodoros Kontogiannis from the NML and the lead author of the paper that resulted from this work, about the group’s findings.

This LCGC blog highlights the ACS SCSC’s initiatives, events, and awards that connect and support the global separation science community across academia, industry, and government.

David S. Hage discusses how recent developments in immobilization chemistry and materials science are enhancing the performance and versatility of affinity-based separations.

David S. Hage shares how his team is applying microfluidics and miniaturized separation systems to improve speed, reproducibility, and real-world applicability in analytical and bioanalytical chemistry.

This past week, LCGC International published a variety of articles on hot topics in separation science. We discuss how mass spectrometry (MS) unveiled new insights into how music modulates protein networks in lipid nanoparticle delivery and how gas chromatography (GC) can be sed to identify aroma types in unburnt cannabis. Also, we make a call for nominations for the 2026 HTC Innovation Award.

Researchers have developed an enhanced LC-MS/MS method capable of quantifying 18 steroids—including key corticosteroid and sex steroid hormones, as well as intermediates involved in corticosteroid synthesis—in plasma and tail samples collected during the transition of tadpoles into frogs.

David S. Hage, James Hewett University Professor at the University of Nebraska–Lincoln, discusses how advances in affinity-based separations are shaping the future of personalized medicine and transforming clinical diagnostics.

Research focused on the cooking process of marinades used headspace solid-phase microextraction gas chromatography-mass spectrometry to analyze changes and volatilization characteristics of flavor compounds at different cooking times.

Sean Jameson, SVP of Business Development at VUV Analytics, discusses the newly released ASTM D8519 method. This method extends established VUV-based hydrocarbon analysis into the pyrolysis oil range, enabling automated, scalable characterization of complex recycled and biomass-derived feedstocks up to C64.

Discover the 2026 HTC Innovation Award, recognizing groundbreaking contributions in separation science and hyphenated techniques by emerging scientists.

A study conducted by a multinational research group investigated the potential of audible sound waves (in the form of music, specifically Pink Floyd’s "Another Brick in the Wall, Part 1") in enhancing nanoparticle neuronal uptake and brain penetration.