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GC–MS Maps PAH Breakdown in Oil Sludge Composting

HPLC-UV Quantifies Thiols in Berry Superfruits

HILIC and the Shift Beyond TFA in GLP-1 Analysis

Conversations with Michael Dong: Reversed-Phase Chromatography: Retention Mechanism of Hydrophobic Interaction

LC–MS/MS Tracks Gel-Delivered Bupivacaine in Dogs

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HILIC VS RP: Separating Impurities in Fatty-Acid-Conjugated siRNAs (Part 2)
In the second part of our interview, Novartis's Martina Lioi talks about using IP-HILIC and RP for lipid-siRNA impurities

LCGC International spoke to David Hage, Sanduni Heenkenda, and Zoe Zingler of the University of Nebraska-Lincoln about how green chemistry principles are reshaping affinity chromatography.

Panelists identify the parameters that make or break peptide method robustness and tech transfer, including temperature, flow rate, and dwell volume.

In Part 2 of "Conversations with Michael Dong," the LCGC column editor discusses HPLC columns for pharmaceutical analysis and the case for short columns.

Gas chromatography-mass spectrometry (GC–MS) shows scarlet macaw feather scent varies by sex and mate status.

Martina Lioi pairs IP-HILIC and RP to map impurities in fatty acid–linked siRNAs

Gas chromatography-mass spectrometry (GC–MS) reveals bisphenol A and other lasting pollutants in Maricá Lagoon (Brazil) sediments.

This week, Chromatography Online covered automated GC-MS/MS testing for phthalates in oils, chemicals hidden in bioplastic packaging, troubleshooting tips for oligonucleotides and GLP-1 peptides, automated glycan profiling, NIST reference materials, and the experience of being the only woman in the laboratory.

Multidimensional chromatography cuts ion suppression in complex environmental samples by separating salts and coeluting compounds from target analytes.

The panel discusses quantitative peptide analysis, including drug substance vs. drug product complexity, recovery, and methionine oxidation risk.

Gas chromatography–quadrupole time-of-flight mass spectrometry (GC–QTOF MS) screening of dust finds 269 contaminants in homes, offices, and schools.

Gas chromatography-mass spectrometry (GC–MS) reveals citral drives inhaled magnolia oil's attack on breast cancer.

The 2026 Gulf Coast Conference (GCC) will be held at the Moody Gardens Convention Center in Galveston, Texas, from October 12–15.

The panel cover protecting peptide recovery, from mobile-phase pH and diluent buffers to inert column hardware.

Henri B. Kagan and Kenso Soai win 2026 Nobel Prize in Chemistry for explaining molecular handedness





















