A non-invasive wearable sampler combined with UHPLC–IMS-HRMS has been developed to identify biomarkers for TB using human skin

When analyzing samples using liquid chromatography–high-resolution mass spectrometry, there are various ways the processes can be improved. Researchers created new methods for prioritizing these strategies.

In the final part of our interview with Michael Shortreed, he shares the most important lessons he would like the next generation of mass spectrometrists to learn.

In the second part of our interview with Michael Shortreed, he reflects on how his work is used in laboratories worldwide and discusses those who mentored him throughout life.

LCGC International's April series for National Cannabis Awareness Month concludes with a discussion with Walter B. Wilson from the National Institute of Standard and Technology’s (NIST’s) Chemical Sciences Division regarding recent research his team conducted investigating chromatographic interferences that can potentially inflate the levels of Δ9-THC in Cannabis sativa plant samples, and possible solutions to avoid this problem.

In the first part of our interview with Michael Shortreed, we discuss his winning the Al Yergey MS Scientist Award and learn about his research on computational methods.

Here is some of the most popular content posted on LCGC International this week.

Come and meet the International Women in Chromatography at HPLC 2025 in Bruges, Belgium.

Aqueous two-phase systems have become more popular as biomanufacturers look to adopt continuous processing. However, there are several uncertainties regarding widespread use of this technique.

The United Kingdom banned menthol as a characteristic flavor in cigarettes in May 2020. Researchers tested cigarettes sold in 2021–2022 for menthol and other characterizing flavors through sensory and chemical testing, using gas chromatography–mass spectrometry (GC–MS) in their research.

LCGC International spoke to Craig Wheelock and Matthew Smith from the Wheelock Laboratory at the Karolinska Institute, Sweden, about a novel desorption electrospray ionization–multiple-reaction-monitoring mass spectrometry (DESI-MRM-MS) workflow his team has developed to spatially map oxylipins in pulmonary tissue.

This article explores the integration of high-resolution ion mobility spectrometry–mass spectrometry (HRIMS-MS) with liquid chromatography (LC) and quadrupole time-of-flight mass spectrometry (QTOF-MS) as a comprehensive workflow for PFAS analysis.

Two-dimensional liquid chromatography (2D-LC) coupled to mass spectrometry (MS) has been used to separate proteins in the venom of the Indian cobra snake.

Ping Wei powder is a type of traditional Chinese medicine used to treat digestive system diseases. Its growth in popularity has led to scientists seeking to properly identify its chemical profile.

Ceftazidime and avibactam are two anti-infective drugs that can prove difficult to analyze in serum. Determining them can assist in therapeutic drug monitoring or pharmacokinetic studies.