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The model context protocol (MCP) layer lets AI run mzmine mass spectrometry workflows; data stays local.

Ultrahigh-performance liquid chromatography–high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) reveals a chemical imbalance behind alcohol-positive milk.

"Perspectives in HPLC" examines 5 long-held HPLC "rules" (mobile phase filtration, routine buffer use, avoiding pH near an analyte's pKa, defaulting to 4.6-mm columns, and relying on AI for early method development), showing with experimental evidence that each is conditional rather than universally true in modern small-molecule drug testing.

In this ninth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explores the reasons why mobile phase filtration is not needed.

Affinity Chromatography for Biopharmaceutical Analysis: A Mini-Review of History, Principles, and Potential Applications
A review of affinity chromatography methods for biopharmaceutical analysis.

Ultrahigh-performance liquid chromatography–ion mobility–quadrupole time-of-flight mass spectrometry (UHPLC–IM–QTOF MS) reveals seasonal chemical fingerprints in Scottish honey.

Markes International’s vacuum-assisted HiSorb extends analyte coverage for gas chromatography.

Gold-enhanced thin-layer chromatography–surface-enhanced Raman scattering (TLC–SERS) identifies toxic aromatics in firefighting water.

ChromSoc’s Data Analytics and AI in Chromatography symposium will debate whether AI could ever replace chromatographers, alongside pharma case studies.

Five years after its founding, the Hungarian developer of centrifugal partition chromatography is making the case that liquid–liquid separation belongs on the analytical bench as well as the production floor.

Liquid chromatography–tandem mass spectrometry (LC-MS/MS) links a teenager's death in Japan to swallowing a fentanyl skin patch.

A two-dimensional gas chromatography (GC×GC) study of 43 volatiles shows hexanal alone cannot gauge hazelnut aging.

Conversations with Michael Dong: Why UV Detection Dominates Pharmaceutical Analysis and Quality Control
In this eighth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor discusses why ultraviolet detection dominates pharmaceutical analysis and quality control.

High-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) was used in a reverse triiodothyronine (rT3) test to separate canine hypothyroidism from illness.

Quantera Analytical’s Terry Bates discusses parallel headspace extraction for gas chromatography-mass spectrometry (GC–MS) and direct analysis in real time–mass spectrometry (DART–MS) analysis.





























