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Hans-Gerd Jansses discusses problems associated with LC–MS peptide identification data with sensory perception and the identification of specific tastants for food analysis.

A non-targeted high-resolution mass spectrometry strategy was developed to detect PFAS in food beyond the limits of conventional targeted methods.A non-targeted high-resolution mass spectrometry strategy was developed to detect PFAS in food beyond the limits of conventional targeted methods. Using a single extract for both approaches, data prioritization and ion mobility mass spectrometry helped identify previously unsuspected PFAS, expanding analytical coverage for food safety monitoring.

Liquid chromatography-mass spectrometry (LC-MS) tracks gut bacteria activity before and after cognitive behavioral therapy treatment for social anxiety disorder.

Mass spectrometry–based techniques, including cross-linking and covalent labeling, were used to show how phosphorylation and oxidation alter alpha-synuclein structure, providing insight into how these modifications may influence aggregation and neurodegenerative disease. LCGC International spoke to Ian Webb, corresponding author of a paper that resulted from this research.

"GC Connections" column editor Nicholas Snow offers a basic GC maintenance tools and supplies overview.

Gas chromatography-mass spectrometry (GC-MS) headspace analysis identifies dimethyl disulfide as a microbial marker in spacecraft wastewater.

ASMS 2026 highlighted AI-driven MS software, faster/deeper proteomics, spatial biology imaging, biopharma characterization tools, PFAS monitoring, and greener instrumentation.

This week’s LCGC International website offerings span AI, food, forensics, and clinical therapy.

Gas chromatography coupled with mass spectrometry and ion mobility spectrometry was used to identify volatile compounds shaped by fermentation time and drying temperature in black tea.

ASMS 2026 highlights a potential paradigm shift in metabolomics, as new evidence suggests many unknown signals are ESI artifacts.

Hans-Gerd Janssen highlights the important innovations and challenges remaining using hyphenated spearation science techniques in food analysis.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reveals fasting alters phthalate levels, with higher exposure linked to type 2 diabetes.

HPLC 2026 session on AI in separations science, covering LC–MS, modelling, peak integration and digital method development.