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Kagan and Soai Win 2026 Nobel Prize in Chemistry for Solving the Mystery of Life's "Handedness"

LC-MS/MS Maps Mycotoxin Patterns in Italian Barley

LC-HRMS Uncovers Hospital Wastewater Pollutants

Highlights from the 55th International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC 2026)

Women in Chromatography: Redefining a Successful Career

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Piotr Alvarez explains how his lab uses 2D-LC to enable MS compatibility with legacy methods and to confirm peak purity through orthogonal separation.

Florian Geistmann succeeded retiring Jürgen Semmler as Shimadzu Europa managing director on October 1.

Liquid chromatography-mass spectrometry (LC-MS) profiling reveals chemical diversity across grapevine varieties.

Liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) link perinatal factors to infant urinary metabolite changes.

This LCGC Blog installment explains how NIST categorizes and certifies reference materials, and why they underpin reliable results in science and medicine.

Automated Workflow Paves Way for High-Throughput Reproducible Operations—Trastuzumab Glycosylation Profiling as a Case Study
Comparing manual and automated N-glycan profiling of a trastuzumab biosimilar, researchers found that both workflows detected the same glycan types, but automation gave more reproducible results (mean CV of about 5.7% vs. 7.95%), making it better suited to high-throughput analysis in biopharmaceutical development.

How can analysts resolve impurities that differ by a single mass unit? Experts discuss deamidation, racemization, HRMS, and 2D-LC for GLP-1 peptides.

"LC Troubleshooting" explores why phosphorothioate oligonucleotides (ONs) diastereomers challenge liquid chromatography.

This new high-performance liquid chromatography (HPLC) method reliably measures cholesterol adsorption in artichoke fiber.

The panel walks through confirming peptide identity–from HRMS and LC–MS/MS sequencing to amino acid analysis and D/L-isomer verification.

Malte Hübschen of the University of Duisburg-Essen (Germany) discusses an automated gas chromatography-tandem mass spectrometry (GC-MS/MS) workflow that improves phthalate detection in tricky oils with LCGC International.

Kinjal Bhatt says belonging comes from team culture, not headcount, while Ina Varfaj's goal as her lab's only woman is making sure she isn't the last.

Liquid chromatography–ion mobility spectrometry–high-resolution mass spectrometry (LC–IMS–HRMS) shows elephant seal pups carry more PFAS than their mothers do.

Gas chromatography–mass spectrometry (GC–MS) and omics profiling distinguish duck and goose foie gras composition.

This week's Chromatography Online highlights include olive waste antioxidant recovery, food and tea analysis, EV isolation, mRNA vaccine purification, perfusion chromatography for oligonucleotides, mass spectrometry in teaching and career advice from “Women in Chromatography.”

















