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The Gains in Peak and Intensity Identification

HPLC Confirms Creatine Uptake in Rainbow Trout

Best of the Week: PFAS Detection, LC Troubleshooting, Deep Learning in Proteomics, and More

LC–MS Validates ML Models for Vaping Nicotine

HTC-19 Insights: RPLC×HILIC–cIMS for Data-independent Profiling of Phenolics: Potential Challenges and Future Developments

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LCGC International spoke with Nikoline Juul Nielsen from the University of Copenhagen, Denmark on the benefits of RPLC×HILIC–cIMS for data-independent profiling of phenolic constituents in plant extracts. In this episode she explores practical aspects of cIMS and the potential for routine analysis.

Wallman explains how spectral library accuracy, retention time prediction, and instrument-specific variation make deep learning essential yet difficult in data-independent acquisition proteomics.

Gas chromatography–mass spectrometry (GC–MS) was used in the profiling of links between gut bacteria and metabolites to myasthenia gravis.

LCGC International spoke with Nikoline Juul Nielsen from the University of Copenhagen, Denmark about the benefits of comprehensive two-dimensional liquid chromatography (RPLC×HILIC)—cyclic ion mobility-time-of-flight mass spectrometry (cIMS) for analyzing plant extracts.

Practical GC in gas chromatography: learn how PEG column bleed affects MS sensitivity, and when polar analytes still quantify reliably.

AI promises to solve cost, labor, and regulatory challenges, but a shortage of deployment expertise means it can create more problems than it solves.

High performance liquid chromatography (HPLC) and inductively coupled plasma mass spectrometry (ICP-MS) reveal how diet and sunlight shape grey parrot nutrient levels.

Discover LC–MS chromatography strategies that tackle PFAS at ppt levels in soil, serum and food, boosting sensitivity, selectivity and confidence.

Learn how TD–GC–MS tracks volatile PFAS in air and emissions, meeting OTM-50 and ASTM D8591 limits for safer compliance.

Wallman details PeptDeepKontext, a model built to predict peptide properties across diverse instruments and PTMs by embracing rather than eliminating inter-laboratory variability.

High performance liquid chromatography (HPLC) reveals sugar, acid, and phenolic differences in varieties of grapes.

Restek's three certified reference material (CRM) mixes deliver all native and labeled furans needed for AOAC/EU-compliant food safety analysis.

Gas chromatography-mass spectrometry (GC-MS) and gas-chromatography with flame ionization detection (GC-FID) identify volatile organic compound (VOC) emissions from yard and food waste compost.

High-performance liquid chromatography (HPLC) reveals how burn pit smoke disrupts blood vessels, lungs, and the brain.

Gas chromatography–mass spectrometry (GC–MS) identifies 27 sugar compounds across sweet corn kernel development.












