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AI/ML Now: Uncertainty-Driven Model-Based Search Methods for Method Development in Liquid Chromatography (Part Two)

AI/ML Now: Uncertainty-Driven Model-Based Search Methods for Method Development in Liquid Chromatography (Part One)

LC–MS Metabolomics Links Blood Molecules to Lupus

Industry Roundup: Waters Posts Strong Third Quarter as LC–MS and Chromatography Consumables Drive Growth, Acquires Ion Mobility Pioneer MOBILion

LC–MS/MS Dried Blood Spot Test for Galactosemia

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Sam Whitmarsh explores how retention-time models handle interlaboratory data, novel chemotypes, unusual phases and ionisable compounds, and what labs need to do to build useful in-house models.


Dual-column ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) reveals urine markers of apple intake lasting 24 hours.

AI/ML Now: Predicting Reversed-Phase LC Retention Using Ensemble Machine Learning and Open Chromatographic Data (Part One)
Sam Whitmarsh describes a practical workflow for predicting reversed-phase LC retention times using ensemble machine learning and open chromatographic data.

This month's LCGC Blog explores the variety of career options that are open to separation scientists.

Optimized preparation and data-independent acquisition (DIA) liquid chromatography–mass spectrometry (LC-MS) detect up to 6500 proteins in laboratory-grown duck.

Directive (EU) 2024/3019 makes drug manufacturers financially responsible for removing pharmaceutical residues from wastewater and introduces stricter, standardized monitoring requirements that are set to increase demand for trace-level analytical expertise.

AOA Dx Chief Scientific Officer Abby McElhinny discusses with LCGC International how the company used high-resolution mass spectrometry-based multi-omics to develop Omira OC, a targeted blood test for early ovarian cancer detection, and how its lipid-based approach is showing promise across endometrial, cervical, and other cancers.

Viktoriia Turkina discusses toxicity prediction for unknown LC–HRMS features using machine learning.

In this final part of "Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor presents a case study of a high-pH separation.

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) shows how processing and storage shape toxins in Nigerian rice.

Ultrahigh-pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF-MS) reveals lipid shifts in acne-prone oily skin of young women.

This week, Chromatography Online.com covered the looming chromatography expertise gap, HPLC myths, steroid and biopharmaceutical separations, AI in the laboratory, and new sample extraction tools.

Gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–tandem mass spectrometry (LC-MS/MS) link tobacco leaf chemistry to cigar taste and burning.

The model context protocol (MCP) layer lets AI run mzmine mass spectrometry workflows; data stays local.

























