Application Notes: Sample Prep

Analysis of Free Steroids and Sulfate Conjugates (Nov 2022)

November 21, 2022

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This app note outlines a highly efficient method for the simultaneous analysis of free and sulfated steroids from urine, plasma, and blood utilizing SPE and LC-MS/MS.

Automated SPE of PFCs from Tap Water

November 15, 2022

Sponsored Content

This application note describes the automation of the isolation of 10 perfluorinated compounds (PFCs) from tap water prior to their analysis by LC–MS.

Analysis of Cannabinoids in Blood

October 24, 2022

Sponsored Content

This application note outlines an extraction method for four natural cannabinoids and two major metabolites of Δ9-THC in blood using Clean Screen® THC SPE column.

Analysis of Free Steroids and Sulfate Conjugates

October 24, 2022

Sponsored Content

A robust analysis method for steroids was developed that can readily be implemented by clinical, forensic, or anti-doping laboratories.

Analysis of Cannabinoids in Urine

October 24, 2022

Sponsored Content

This application note features a unique, simple, and robust solid-phase extraction method for cannabinoids in urine followed by analysis with LC–MS/MS.

Extraction of Novel Synthetic 2-Benzylbenzimidazole Opioid Compounds "Nitazenes"

October 24, 2022

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This application note introduces a simple targeted extraction method for the analysis of nine nitazene compounds from urine and blood using the Clean Screen® DAU column.

On-Column Digest Followed by SPE Desalting

October 14, 2022

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Tecan’s proprietary NBE™ format enables digestion or incubation AND elution in a single SPE column. Read this app note to learn more and streamline your workflows!

An Optimized Protocol for the Clean-up of Oligonucleotides

October 11, 2022

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The Clarity OTX 2 mg/well format is used for the isolation, characterization, and quantitation of current antisense oligonucleotide therapeutics from small biological fluids.

Comparing Supported Liquid Extraction and Liquid–Liquid Extraction: for extracting Acidic, Basic, and Neutral Analytes from Plasma

September 21, 2022

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Advantages of using a supported liquid extraction (SLE) over liquid–liquid extraction (LLE) method for extracting a range of analytes from pig plasma.

Efficient Peptide Desalting Using Tecan’s Proprietary NBE™ Columns

September 19, 2022

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Tecan’s proprietary NBE format SPE columns enable desalting in the column before peptide extraction. Read this app note to see how Tecan can accelerate your workflows!