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Tony Taylor is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LCâMS and GCâMS for materials characterization, especially in the field of extractables and leachables analysis.

Articles

In this LCGC blog, some words of wisdom are offered to help one avoid that panic situation of having to change the GC column or delay the analytical results. 

GC Column Killers!

Understanding the relationship between selectivity and retention is key to realizing excellent gas chromatographic separations.

How Chemistry Determines Separations: Influence of Selectivity on Resolution

What is the relationship between selectivity and resolution?

How Chemistry Determines Separations: The Influence of Selectivity on Resolution

Two-dimensional gas chromatography (GC×GC) and chemometrics are leading the way in new strategies on multivariate data analysis. Using GC×GC in untargeted analysis reveals how far the technique has advanced the field of separation science.

Revisiting the Fundamentals of Untargeted Data Analysis with Comprehensive Two-Dimensional Gas Chromatography (GC×GC): With Great Peak Capacity, There Must Also Come Great Responsibility

You're invited to publicize your 2022–2023 new product introductions in LCGC. Here's how to get your products included.

LCGC 2023 New Product Review – Call For Submissions

By reviewing the basic thermodynamics underlying GC separations, we see how it impacts retention and method development in GC analysis.

Using Thermodynamics and Simulations to Understand Selectivity and Retention in Gas Chromatography

Novel nontargeted analysis applications in two-dimensional gas chromatography–mass spectrometry (GC×GC–MS) and GC–high‑resolution (HR)MS have enabled the discovery of new contaminants. Now, the next frontier is nontargeted analysis for the elucidation of the mechanisms of (bio)chemical reactions in complex samples, such as the biodegradation of organics in water and soils or the conversion of plastics into oils. GC has the potential to contribute greatly to the optimization of these processes and therefore make a real contribution to net zero and circular economy agendas.

“Signature” Analysis of Complex Environmental Samples Using Nontargeted Two‑Dimensional Gas Chromatography

In this instalment, we review the basic thermodynamics underlying separation in GC, and we see how this impacts selectivity and retention.


Using Thermodynamics and Simulations to Understand Selectivity and Retention in GC 

Elinor Hughes obtained her B.Sc. in chemistry and Ph.D. in organic chemistry at Bangor University, UK. After working for a chemical manufacturing company for three years, she moved to the Royal Society of Chemistry where she worked in journals publishing for six years and on Chemistry World magazine for four years. This was followed by five years as a freelance copyeditor and science writer. Her current role is technical copywriter at Markes International.

Immersive sorptive extraction coupled with comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry (GC×GC–TOF-MS) was used to compare flavour profiles from popular brand soft drinks with those of imitation products.

Comparing the Flavour Profiles of Soft Drink Brands Using Immersive Sorptive Extraction, GC×GC–TOF-MS, and Chemometrics

The Column interviewed Maiken Ueland, an ARC discovery early career research fellow at the Centre for Forensic Science and deputy director of The Australian Facility for Taphonomic Experimental Research (AFTER) at the University of Technology Sydney in Australia, on her work in forensic taphonomy, where she uses analytical, biochemical, and spectroscopic techniques to conduct human post-mortem investigations.

Gas Chromatography (GC) | Topics