Application Notes

Articles

In this application note high resolution SCX was coupled directly to an ultrasensitive online native MS using YMC’s BioPro IEX SF to analyse mAb charge variants. 

Native online SCX-MS of monoclonal antibodies

This note demonstrates a novel, easy-to-use, intelligent tandem nanoLC-MS setup capable of 100% MS use that is compatible with the  Sonation double-barrel nano ESI source.

Maximize Productivity in Proteome Profiling

Introducing 3 unique particle platforms for SPE that offer additional cleanliness, recovery and accuracy for industry specific applications.  Each mini application guide displays an application for each type of SPE solution. 

Solid Phase Extraction for Food Samples

Solid Phase Extraction for Bioanalytical Samples

Analysis of GHB demands for an analytical procedure that is quick, efficient, and one that preserves the authenticity of the sample. A method for the quantitation of GHB in human blood is presented using SPE with LC-MS/MS analysis.

Analysis of Gamma-Hydroxybutyrate (GHB) in Whole Blood Using Quicker SPE and LC-MS/MS

A fast and efficient SPE sorbent, Strata-X PRO, was chosen to extract a panel of acids, neutrals, and bases from plasma to reduce the number of steps in the clean-up.

Comparison of SPE Products for the Extraction of Acids, Neutrals, and Bases from Plasma by LC–MS/MS

This application focuses on developing a rapid SPE and LC-MS/MS method for the quantitative analysis of uracil and its two homologues from human serum.

A Fast SPE Method for Uracil, 5,6-Dihydrouracil and 5-Fluorouracil from Human Serum by LC-MS/MS

In this application, an SPE method is implemented for a panel of pain relievers to produce acceptable results to offer an alternative solution for high recoveries and to reduce matrix effects.

Pain Relievers from Plasma Using Rapid SPE Products

In this panel of veterninary drugs from a milk sample, SPE displays an improved solution over traditional protein precipitation methods and other types of SPE, due to clean up efficiency, all while maintaining a rapid and fast analysis time.

Application Notes: LC-MS