Application Notes: LC-MS

LC-MS Analysis of 33 PFAS Compounds in 5 minutes

December 13, 2022

The new Ascentis® Express PFAS HPLC and delay columns allow the highly efficient separation of 33 PFAS compounds in 5 minutes with reduced background contamination.

Successful and Stress-Free LC Method Transfers (Nov 2022)

November 10, 2022

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Go ahead, take the stress out of your LC method transfer journey with our free master guide. Features a compilation of proven techniques to help you succeed.

Overcoming the Challenges of Liquid Chromatography Method Transfer: A CDMO Perspective (Nov 2022)

November 10, 2022

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Learn how to transfer your LC methods the right way. A short case study with helpful guidance on how to transfer compendial methods, without needing revalidation.

Tandem UHPLC for High-Throughput Peptide Mapping

September 21, 2022

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This article demonstrates how you can accelerate peptide mapping analyses with Tandem LC-MS workflows by reducing downtime from column reconditioning in gradient runs.

Top HPLC Methods for Profiling PS80

September 21, 2022

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This application note provides a reliable HPLC method for profiling PS80 samples to help you maintain drug consistency and quality across every production batch.

Fast and Rugged Direct Analysis of Polar Pesticides in Spinach

September 20, 2022

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This fast, simple LC-MS/MS workflow for the direct analysis of polar pesticides in spinach provides good retention and peak shape over hundreds of matrix injections.

PFAS Testing Guide: Wastewater, Soil, and Sediments

September 19, 2022

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Application guide to advanced sample preparation for chromatography analysis and mass spectrometry techniques for PFAS's more difficult matrices.

Increased Productivity, High Accuracy, and Precision in the Determination of 18 PFAS by EPA 537.1

September 19, 2022

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Laboratory productivity increase is demonstrated using an SDVB polymer SPE and C18 column selectivity.

PFAS Interlaboratory Study from Potable and Non-potable Water Samples

September 19, 2022

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Multiple laboratories applied method EPA 537.1 and 533 for the extraction of PFAS in pristine non-potable water and source water assessment.

Managing Cross-contamination in PFAS Sampling, Extraction, and Analysis

September 19, 2022

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PFAS experts provide insight on workflow considerations on how to manage and prevent cross-contamination to ensure quality analysis.