Application Notes

Articles

A SLE application for acids (THC-COOH), neutrals (barbiturates), and bases (Norbuprenorphine and Buprenorphine) from a urine matrix containing β-glucuronidase followed by two LC-MS/MS methods.


Acids, Neutrals and Bases Using Novum Simplified Liquid Extraction (SLE)

Estrone, beta-estradiol, and estriol were derivatized from plasma using Novum PRO 96-Well Plates SLE for less background noise and cleaner samples post sample preparation.


Separation of Low Level Estrogen Analytes from Plasma by LC-MS/MS Analysis in Conjunction with Novum PRO Simplified Liquid Extraction (SLE)

This application focuses on developing a rapid SPE and LC-MS/MS method for the quantitative analysis of uracil and its two homologues from human serum


A Fast SPE Method for Uracil, 5,6-Dihydrouracil and 5-Fluorouracil from Human Serum by LC-MS/MS v2

Testosterone was isolated from plasma using Novum PRO 96-Well Plates SLE sample preparation.


Isolation of Low Level Testosterone from Plasma by LC-MS/MS Analysis in Conjunction with Novum PRO SLE

Analysis of GHB demands for an analytical procedure that is quick, efficient, and one that preserves the authenticity of the sample. A method for the quantitation of GHB in human blood is presented using SPE with LC-MS/MS analysis.


Analysis of Gamma-Hydroxybutyrate (GHB) in Whole Blood Using Quicker SPE and LC-MS/MS v2

In this application, an SPE method is implemented for a panel of pain relievers to produce acceptable results to offer an alternative solution for high recoveries and to reduce matrix effects.

Pain Relievers from Plasma Using Rapid SPE Products v2

A sensitive method for analyzing nicotine and metabolites using SLE to increase recoveries, while still displaying accuracy, precision and linearity.


A Sensitive Extraction Method for Nicotine and Metabolites from Urine using SLE

In this panel of veterninary drugs from a milk sample, SPE displays an improved solution over traditional protein precipitation methods and other types of SPE, due to clean up efficiency, all while maintaining a rapid and fast analysis time.

Utilizing a Rapid, Two-Step Method for the Clean-Up of Veterinary Drugs in Milk Using Strata®-X PRO Solid Phase Extraction (SPE) v2

Peptides are extracted from plasma comparing Strata-X PRO SPE to two types of ion exchange polymeric sorbent. Strata-X PRO provides high recoveries with a fast and effective clean-up method.

High Recovery of Peptides from Plasma Using Different SPE Sorbents v2

Revolutionize your bioanalytical sample preparation. Search application notes by your compounds of interest, application area, SOLA chemistry phases, or SOLA formats.

Application Notes: LC-MS