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New sample preparation workflows for intact proteins in biological matrices are needed. We hope that others will join in this important field of research.

The Crucial Step in Every Analytical Workflow: Sample Preparation—Are We Ready For a Growing Area of Intact Protein Analysis?

Paul Bohn, the Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering at the University of Notre Dame, is the 2022 recipient of the Society for Electroanalytical Chemistry (SEAC) Charles N. Reilley Award. 

Paul Bohn Receives SEAC Charles N. Reilley Award

Our annual review of new gas chromatography products.

New Gas Chromatography Products for 2021–2022

Our annual review of new high performance liquid chromatography instruments, mass spectrometry systems, and data processing software.

New HPLC, MS, and CDS Products Introduced in 2021–2022: A Brief Review

Kevin A. Schug is a Full Professor and Shimadzu Distinguished Professor of Analytical Chemistry in the Department of Chemistry & Biochemistry at The University of Texas (UT) at Arlington. He joined the faculty at UT Arlington in 2005 after completing a Ph.D. in Chemistry at Virginia Tech under the direction of Prof. Harold M. McNair and a post-doctoral fellowship at the University of Vienna under Prof. Wolfgang Lindner. Research in the Schug group spans fundamental and applied areas of separation science and mass spectrometry. Schug was named the LCGC Emerging Leader in Chromatography in 2009, and most recently has been named the 2012 American Chemical Society Division of Analytical Chemistry Young Investigator in Separation Science awardee.

Zacariah L. Hildenbrand is a partner of Medusa Analytical. He sits on the scientific advisory board of the Collaborative Laboratories for Environmental Analysis and Remediation (CLEAR), is a director of the Curtis Mathes Corporation (OTC:TLED), and is Research Professor at the University of Texas at El Paso, USA. Hildenbrand’s research has produced more than 60 peer-reviewed scientific journal articles and textbook chapters. He is regarded as an expert in point source attribution and has participated in some of the highest profile oil and gas contamination cases across the United States.

Reviewing your contract laboratory’s QA/QC protocols can reveal much about the accuracy of the data the lab generates. Here is what to look for.

Laboratory Accreditation Is Not a Cloak of Infallibility

An undeniable effect of the COVID-19 pandemic is that we have learned how to adapt (quickly) to sudden changes. 

The LCGC Blog: Mentorship in the Time of COVID-19: Finding the Silver Lining and Announcing ACS SCSC Initiatives 

Compact instrumentation offers important advantages for many workflows, as illustrated by these examples.

Exploring the Implementation of Compact Chromatographic Instrumentation in Common Analytical Workflows

Tony Taylor is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LCâMS and GCâMS for materials characterization, especially in the field of extractables and leachables analysis.

The quadrupole mass analyzing device is now accessible to many analytical chemists as a detector in either HPLC or GC instruments due to their increasingly accessible price point. While it’s not vital that we understand the working principle of these detectors, insight into their design and operation can help enormously when planning or optimizing analyses or troubleshooting issues. 

The LCGC Blog: The Beauty of the Quadrupole Mass Analyzer

Computer-enabled technology approaches can mitigate the impact of aging instruments and instrument differences—leading to more robust, lower-maintenance analysis in industrial settings.

Controlling Retention Time Drift in Industrial Chromatography Settings

Everyone who is reading this column is interested in chromatography, and I want to shine a light on the industrial side of the application space. 

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