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May 24, 2022
Separations science within microfluidics has already begun to make significant impact across any number of fields. But many times they are embedded within a larger system—their importance hidden or minimized.
May 09, 2022
In this next installment of our “Critical Evaluation” series, we will examine gas chromatography methods which use mass spectrometric detection (GC–MS).
May 06, 2022
By using MS-based techniques, thousands of metabolites can be measured.
May 01, 2022
Employing ion mobility at atmospheric pressure without vacuum enables coupling to high-resolution mass analyzers. High performance ion mobility–orbital trap mass spectrometry (HPIM-OT-MS) is a useful alternative for separating isomers, such as isomeric metabolites seen in drug discovery.
Multidimensional liquid chromatography (MDLC) methods have revolutionized the characterization of complex drug modalities like antibodies–drug conjugates, antisense oligonucleotides, and small interfering RNA therapeutics.
The study of the thermal behavior and pyrolysis products of these terpenoids could possibly suggest flavor precursors that could be used to provide specific flavors.
Measuring volatile phenols in wine is essential in ensuring superior wine quality. A new analytical technique, called solid-phase mesh-enhanced sorption from headspace (SPMESH), was modified with direct immersion (DI) conditions and coupled to direct analysis in real time–mass spectrometry (DART–MS) to be used to detect smoke taint in winemaking.
High resolution time-of-flight mass spectrometry (HR-TOF-MS) with a novel multimode ionization source together with enhanced chromatographic resolution can successfully detect and identify pollutants in household dust samples. Here’s how.
April 01, 2022
Our annual review of new high performance liquid chromatography instruments, mass spectrometry systems, and data processing software.
Newer direct-injection mass spectrometry techniques can improve real-time monitoring of volatile organic compounds.