Application Notes

Articles

Discover a reliable and robust HPLC method to separate Δ10-THC and Δ6a,10a-THC isomers produced from Δ9-THC degradation using a chiral HPLC stationary phase.


Differentiating Four THC Stereoisomers

Daicel’s CHIRALPAK® IJ gives access to an expanded range of solvents, which yields new separations not previously achievable on the coated CHIRALCEL® OJ.

Separation of 2-Phenylbutyrophenone on Daicel’s new CHIRALPAK® IJ (EU)

This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and hydrobenzoin as a test compound.

SFC Achiral Separation Utilising achiral Column

DAICEL’s CHIRALPAK® sub-2 µm columns yield sub 30-second chiral separations of Thalidomide and Naproxen under SFC conditions.

Ultra-fast Chiral SFC Separations

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants.


Multi-Attribute Analysis of Monoclonal Antibodies

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants.

This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and Hydrobenzoin as a test compound.

SFC Achiral Separation Utilizing a Chiral Column

Daicel’s CHIRALPAK® IF proven to perform the difficult separations of cannabinoids Δ8-THC and Δ9-THC.

Separation of the Enantiomers of (+/-) Δ8-THC and (+/-) Δ9-THC

Amyloid β proteins are highly hydrophobic and can form aggregates. The analysis of 4 Aβ using YMC-Triart Bio C4 with larger pore and lower hydrophobicity is presented. 

Challenging analysis of Amyloid β proteins

Successful separations of the enantiomers of 3,3’-substituted BINOLs and their corresponding protected derivatives were obtained on the RegisPack® chiral stationary phase (CSP) from Regis Technologies, Inc.

Application Notes: Chiral