The Column-09-06-2013

Market Profile: Continuous Flow Analysis and Discrete Analysers

This article examines the problem of dermorphin doping in horse racing and presents an effective method for its detection using LC–MS TQ.

Kevin A. Schug, professor at the University of Texas, Arlington (Texas, USA) and LCGC North America EAB member, has led a team to survey and assess the impact of natural gas extraction from shale, also known as "fracking", on nearby water sources. The results of the assessment were recently published in the journal Environmental Science & Technology.1

This article reviews some of the main developments that have led to recent advances in liquid chromatography–mass spectrometry (LC–MS).

Choosing proper tubing connections throughout the entire system, especially when capillary tubing is used, can dramatically improve the level of sensitivity and quality of data obtained with most LC–MS systems.

A German/Chinese team led by Rainer Lehmann, of the University of Tuebingen (Tuebingen, Germany) and Guowang Xu, of the DICP (Dalian, China), has developed a method of simultaneously extracting metabolites and lipids using methyl tert-butyl ether (MTBE) from single small tissue samples for analysis by ultrahigh-pressure liquid chromatography–mass spectrometry (UHPLC?MS).