Electrochemical Reduction of Disulfide Bonds for On-line LC-MS
With Antec Scientific’s new ground-breaking µ-PrepCell-SS, electrochemical reduction of disulfide bonds in peptides, proteins, mAbs, and other biopharmaceuticals becomes possible routinely in LC-MS workflows. • Fast and efficient reduction of S-S bonds • Robust on-line reduction in top-down and bottom-up Proteomics • Reagent free, no interfering DTT or TCEP, ideal for HDXMS • Superior peptide sequencing and S-S bond assignment
Is “right first time, every time” a pipedream for metabolite identification by LC-MS?
March 18th 2025The dream state If we lived in an ideal world, it would be possible to unambiguously identify metabolites using a single analytical experiment. This analytical technique would need to be efficient and easily generate the information needed from a routine assay that is also robust, enabling confident decision-making during drug discovery. At SCIEX, we believe that metabolite identification using the ZenoTOF 7600 system gets close to this dream state.
