Improving USP Monograph Analysis Time Through Scaling by N on an HPLC System Using CORTECS Premier Columns (Oct 2025)

n this application note, a USP monograph is modernized to a shorter column using 5 µm particles, which can be allowable under USP <621> as long as the N value is within the guidelines. By using highly efficient CORTECS 5 μm particles, this type of modernization is possible and reductions in solvent usage and run times are achieved