News|Articles|October 13, 2025
Improving USP Monograph Analysis Time Through Scaling by N on an HPLC System Using CORTECS Premier Columns (Oct 2025)
Author(s)Waters Corporation
Key Takeaways
n this application note, a USP monograph is modernized to a shorter column using 5 µm particles, which can be allowable under USP <621> as long as the N value is within the guidelines. By using highly efficient CORTECS 5 μm particles, this type of modernization is possible and reductions in solvent usage and run times are achieved
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