LCGC UST
|Articles|August 5, 2011

Column

  • The Column-08-05-2011
  • Volume 7
  • Issue 14

Introducing High-Definition GC-MS

Janet Kelsey speaks to Alun Cole, director of ALMSCO International, to find out more about GC-MS and the potential it offers for high-definition screening.

In this issue, we turn our attention to the technique of GC–MS and the potential it offers for high-definition screening. Janet Kelsey of The Column spoke to Alun Cole, director of ALMSCO International, Llantrisant, UK, to find out more about this versatile technique.

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Related to this article

Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.