Christina M. Sorgen

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Evaluation of Polar-Embedded and Polar-Endcapped C12-C18 Stationary Phase Vulnerabilities Toward Highly Nucleophilic Compounds: A Case Study

Christina M. Sorgen;Larry J. Burge

August 1st 2005

Here the authors discuss an ion-pair, gradient HPLC method, developed for cycloserine-related substances using a polar, amide-embedded C18 column. Other polar-embedded and polar-edcapped columns are evaluated in equivalence studies.

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