Dr. Detlef Jensen, Thermo Fisher Scientific

See how combustion ion chromatography can be used to determine total organic fluorine in textiles as manufacturers respond to evolving PFAS requirements. This application proof note demonstrates a C-IC workflow using the Cindion Combustion Ion Chromatography System and Dionex Inuvion IC system.

PFAS testing requirements vary by matrix and analytical goal. See workflows spanning sample preparation, targeted LC-MS/MS analysis, combustion ion chromatography, high-resolution mass spectrometry and data processing for water, soil and other challenging samples. The guide also compares approaches for known PFAS quantitation and unknown screening.

See how Professor Lee Ferguson's laboratory at Duke University combines high-resolution mass spectrometry, Compound Discoverer software and advanced cheminformatics to investigate complex PFAS mixtures. The work includes a spectral library of more than 46,000 known and predicted compounds to support identification of known, unexpected and emerging PFAS.

Get an overview of PFAS sources, environmental pathways and analytical approaches across industrial and environmental applications. This roadmap connects routine targeted testing with broader investigational workflows, including sample preparation, LC-MS/MS, combustion ion chromatography and high-resolution mass spectrometry.

Explore a semi-automated approach to PFAS analysis in soil designed to meet US EPA Method 1633A performance requirements. The workflow automates extraction and sample clean-up to increase throughput, reduce manual handling and help minimize opportunities for error and PFAS contamination.

Explore the use of adsorbable organic fluorine and combustion ion chromatography to screen for PFAS in wastewater. This application note presents results from the EPA Method 1621 multi-laboratory collaboration study, including practical guidance for adsorption, combustion, ion chromatography and method implementation.

Complex water and wastewater matrices can create challenges for routine analytical testing. Explore standardized ion chromatography methods, key ISO and ASTM standards, and analytical workflow considerations for determining ionic and ionizable contaminants across industrial and other water matrices.