Malvern Instruments Ltd. | Authors


Characterization of IgG monomers & their aggregates

Two antibody samples were characterized using column calibration and multi-detection SEC, and the results compared to show how multi-detection SEC provides more accurate data and a more complete characterization of the protein mixtures under study.

Cellulose Derivatives: The Effect of Molecular Weight and Structure on Performance

A variety of aqueous (water-soluble) cellulose derivatives were characterized using the OMNISEC triple detection GPC/SEC system which revealed subtle, yet distinct differences between them. The differences described in this application note could be used in the pharmaceutical industry to correlate their molecular properties with performance.