All PublicationsLCGC InternationalLCGC North AmericaLCGC EuropeLCGC Asia PacificLCGC SupplementsThe ColumnE-BooksThe Application Notebook
Columns
All NewsInterviews
All App NotesBiological, Medical, and ClinicalBiopharmaceuticalsCannabisChiralEnvironmentalFood and BeverageGCGC-MSGeneralIndustrialLCLC-MSMedical/BiologicalMisc TechniquesPharmaceuticalsPolymersSample PrepSize-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)
Conference CoverageConference Listing
All WebcastsChromAcademy
ProductsE-BooksChromTubeEventsAnalytically Speaking PodcastPodcastsPodcast SeriesSponsored VideosQ&AsSponsored ContentContent Engagement HubsTips & TricksIndustry InsightsCareer OpportunitiesPeer Exchange
DirectorySubscribe
Analytical Instrumentation
Analytical Theory
Biological, Medical, and Clinical Analysis
Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
UHPLC
Web of Science
Spotlight -
  • Agilent Technologies Battery Summit
  • Advances in Gas Chromatography
  • The 2025 LCGC International PFAS Summit
IS1

  • Applied Clinical Trials

  • BioPharm International

  • Cannabis Science and Technology

  • Chromatography Online

  • Nutritional Outlook

  • Pharmaceutical Commerce

  • Pharmaceutical Executive

  • Pharm Tech

  • Spectroscopy Online

  • Turbo Machinery Magazine

Analytical Instrumentation
Analytical Theory
Biological, Medical, and Clinical Analysis
Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
UHPLC
Web of Science
IS1

  • Applied Clinical Trials

  • BioPharm International

  • Cannabis Science and Technology

  • Chromatography Online

  • Nutritional Outlook

  • Pharmaceutical Commerce

  • Pharmaceutical Executive

  • Pharm Tech

  • Spectroscopy Online

  • Turbo Machinery Magazine

    • Columns
    • Directory
    • Subscribe
Advertisement

Ron Bonner

home / authors / ron-bonner

Articles

electrical lightning bolt representing an ion

The Origin and Implications of Artifact Ions in Bioanalytical LC–MS

Ron Bonner;Gérard Hopfgartner
July 1st 2022

Although well known, the extent of adduct ion formation in LC–ESI-MS/MS, and the implications for quantitative analysis and analyte characterization are not fully appreciated. We explore this problem and explain the implications for reproducibility, quantitative and qualitative analyses, and DDA and DIA.

Latest Updated Articles

Your Lab Deserves a Technology Upgrade
Published: March 14th 2025 | Updated: March 28th 2025
Your Lab Deserves a Technology Upgrade
Analyzing Organic Acids in Fruit-Based Kombucha Analogues Using HPLC
Published: November 15th 2024 | Updated: November 19th 2024
Analyzing Organic Acids in Fruit-Based Kombucha Analogues Using HPLC
LC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles
Published: November 18th 2024 | Updated: November 19th 2024
LC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles
Technology Trends in Separation Science: Data Handling
Published: July 3rd 2024 | Updated: July 8th 2024
Technology Trends in Separation Science: Data Handling
Merck Curiosity Cube 2025 © Image courtesy of Merck KGaA
Published: May 9th 2025 | Updated: May 13th 2025
Merck Launches 2025 Global Curiosity Cube Tour to Expand STEM Education Access
University of Oklahoma and UC Davis Researchers Probe Lipidomic Profiles with RP-LC–HRMS/MS
Published: May 6th 2025 | Updated: May 13th 2025
University of Oklahoma and UC Davis Researchers Probe Lipidomic Profiles with RP-LC–HRMS/MS
About
Advertise
Author Guidelines
Contact Us
Editorial Advisory Board
Ethics Policy
Do Not Sell My Personal Information
Privacy Policy
Permissions
Subscriptions
Terms and Conditions
Contact Info

2 Commerce Drive
Cranbury, NJ 08512

609-716-7777

© 2025 MJH Life Sciences

All rights reserved.
Home
About Us
News