Theodore Sana

home / authors / theodore-sana

Articles

i4-782412-1408600800098.jpg

Nontargeted, Discovery-Based Profiling of the Yeast Metabolome Using QTOF LC–MS and LC–MS-MS

Stefan Jenkins;Steven M. Fischer;Theodore Sana
July 1st 2012

A discovery-based, untargeted metabolomics analysis of hundreds of yeast metabolites under robust, controlled extraction conditions followed by identification is described.

i4-716436-1416911780171.jpg

Metabolomics Workflows: Combining Untargeted Discovery-Based and Targeted Confirmation Approaches for Mining Metabolomics Data

Theodore Sana;Shane E. Tichy;Steve Fischer
March 1st 2011

The metabolomics workflow described here combines untargeted (discovery) quadrupole time-of-flight (Q-TOF) liquid chromatography–mass spectrometry (LC–MS), targeted (confirmation) triple-quadrupole LC–MS-MS, and sophisticated data mining as an effective means to elucidate metabolite changes.

Latest Updated Articles

Technology Trends in Separation Science: Data Handling
Published: July 3rd 2024 | Updated: July 8th 2024
Technology Trends in Separation Science: Data Handling
Human monoclonal antibody to fight cancer | Image Credit: © Yuriy - stock.adobe.com
Published: June 28th 2024 | Updated: October 24th 2024
Analysis of Therapeutic Monoclonal Antibodies Using a Platform Size Exclusion-HPLC Method
Virus protection. Vaccine search. Antibodies and viral infection. Immune defense of the body. Attack on antigens 3D illustration By Siarhei - stock.adobe.com
Published: July 16th 2024 | Updated: October 24th 2024
Characterization of Product Related Variants in Therapeutic Monoclonal Antibodies
Chromatograph with glass sample bottles | Image Credit: © JJIMAGE - stock.adobe.com
Published: September 10th 2024 | Updated: October 24th 2024
Analytical Method Lifecycle of SFC Methods from Development Use to Routine QC Implementation; Supporting Small Molecule R&D and Commercialization
Glass vial, pipette and woman scientist in laboratory for medical study, research or experiment. Test tube, dropper and professional female person with chemical liquid for pharmaceutical innovation. | Image Credit: © peopleimages.com - stock.adobe.com
Published: September 16th 2024 | Updated: October 24th 2024
Are You Sure You Understand USP <621>?
Scientist moved the vial of sample out from the tray autosampler of the Liquid Chromatography Mass Spectrometer LC/MS after the analysis was complete. | Image Credit: © S. Singha - stock.adobe.com
Published: September 13th 2024 | Updated: October 24th 2024
In-Loop Analyte Degradation in Two-Dimensional Liquid Chromatography: Example and Solutions