Three-dimensional (3D) printing shows promise for creating stationary phases with tailored geometries. We present a method that overcomes limitations of other approaches, and can produce columns with a feature resolution of 10 μm.
For approximately a decade, 3D-printed columns have been hailed as the future of LC. However, the resolution of typical printing methods has fallen short of the requirements to make an effective analytical or preparative-scale column. In this article, we describe a new 3D-printing method that can create large-volume columns with a feature resolution of 10 μm.