LCGC Europe-04-01-2014

Some attributes of large molecules make them behave differently from small molecules in reversed-phase separations.

This installment highlights some of the new HPLC systems, modules, accessories, and related technology introduced at Pittcon this year.

The variation in selectivity of aromatic hydrocarbons with bisubstituted polar groups is investigated in systems consisting of C18 stationary phase and ternary eluents. The solutions of the ternary eluents were obtained by mixing binary solvents (organic modifier + water) of similar eluent strength. Acetonitrile, methanol and tetrahydrofuran were the organic modifiers applied. The influence of the organic solvent type and its concentration in the ternary mobile phase on retention and selectivity of the solutes is discussed. An approach previously presented by our group was adapted to explain the selectivity changes.

The potential to accurately and rapidly measure hundreds of individual molecular species provides novel opportunities for food science and nutrition. For food and nutrition researchers, metabolomics, the screening of small-molecule metabolites, enables the molecular fingerprinting of food components. This article describes the various applications, strategies, and tools related to metabolomics in food analysis.

Part 1 of our annual report on new products introduced at Pittcon. This month, columns are highlighted, covering HPLC/UHPLC columns, packings, and related products.

Event News

Click the title above to open the LCGC Europe April 2014 regular issue, Vol 27 No 4, in an interactive PDF format.