The Agilent 1290 Infinity II UHPLC, an Agilent 6545 Q-TOF/MS, and Agilent MassHunter BioConfirm B.08.00 software was used for accurate disulfide bond mapping.
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.