News|Videos|October 22, 2026

Conversations with Michael Dong: Why 2.1-mm i.d. Columns Are Preferred for Pharmaceutical Quality Control

In this seventh part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why 2.1-mm i.d. columns are less preferred for pharmaceutical quality control.

Michael Dong, editor of LCGC International's "Perspectives in HPLC" column, has launched a video series in 2026 called "HPLC in Pharmaceutical Analysis," which explores how the technique is used in the pharmaceutical field.

In celebration of National Chemistry Week at the end of October, ChromatographyOnline.com is pleased to share "Conversations with Michael Dong" this month, featuring highlights from the series. We encourage readers to watch the full series, a free and thorough educational introduction to HPLC for pharmaceutical laboratory professionals at every stage of their careers who want to brush up on the basics. No matter how much experience you have with the technique, you're sure to come away with useful tips for sharpening your skills.

In this installment, Dong explains why 2.1-mm i.d. columns are less preferred for pharmaceutical quality control.

The entire video, “Why should you use a 3-mm i.d. column” can be accessed at https://www.youtube.com/watch?v=J77WVUYx-Yw


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