LCGC UST
News|Articles|January 28, 2025

Determination of 3-MCPD, 2-MCPD and Glycidol in oil and fat by ISO 18363-4 Zwagerman/Overman

Author(s)GERSTEL

Fully automated method for 3-MCPD, 2-MCPD and Glycidol determination in Edible Oil and Fat based on ISO 18363-4 - Zwagerman/Overman with validation data. A recent upgrade to PTV injection has further improved the quality and robustness of results. Fatty acid esters of 3- and 2-monochloropropanediol (3-MCPD-e, 2-MCPD-e) and glycidol (Gly-e) are process contaminants that are formed, for example, when edible oils and fats are refined. After ester cleavage during digestion in the human body they pose a relevant health risk and therefore need to be determined in edible oils and fats and in fat containing food.


Related to this article

Best of the Week: From Olive Waste to mRNA Vaccines
This week's Chromatography Online highlights include olive waste antioxidant recovery, food and tea analysis, EV isolation, mRNA vaccine purification, perfusion chromatography for oligonucleotides, mass spectrometry in teaching and career advice from “Women in Chromatography.”