Fully automated method for 3-MCPD, 2-MCPD and Glycidol determination in Edible Oil and Fat based on ISO 18363-4 - Zwagerman/Overman with validation data. A recent upgrade to PTV injection has further improved the quality and robustness of results. Fatty acid esters of 3- and 2-monochloropropanediol (3-MCPD-e, 2-MCPD-e) and glycidol (Gly-e) are process contaminants that are formed, for example, when edible oils and fats are refined. After ester cleavage during digestion in the human body they pose a relevant health risk and therefore need to be determined in edible oils and fats and in fat containing food.
This week, Chromatography Online explored how the technique is advancing wastewater drug monitoring, siRNA method development, and food safety testing, with previews of RAFA 2026 and a return to HPLC fundamentals with Michael Dong.
In this seventh part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why 2.1-mm i.d. columns are less preferred for pharmaceutical quality control.
Ultrahigh-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF-MS) shows how soaking and cooking break down soybean fats.
Nicolai Zederkopff explores chromatography’s role to help implement the maximum tolerable level (MTL) framework for food adulteration to translate analytical results into compliance decisions.