Growing concern over artificial sweeteners has underscored the need to better understand their
impact on human metabolism and health. Researchers at the University of Applied Sciences and Arts
Northwestern Switzerland (FHNW) have developed a robust workflow to detect sugar alcohols and related
metabolites in biological samples. This article highlights their latest findings and demonstrates how GC–
MS/MS, in combination with automated sample preparation and dried blood spot (DBS) analysis, is evolving
into a powerful approach for studying sweetener metabolism in a holistic, system-wide context.
Liquid chromatography–ion mobility spectrometry–high-resolution mass spectrometry (LC–IMS–HRMS) shows elephant seal pups carry more PFAS than their mothers do.
This week's Chromatography Online highlights include olive waste antioxidant recovery, food and tea analysis, EV isolation, mRNA vaccine purification, perfusion chromatography for oligonucleotides, mass spectrometry in teaching and career advice from “Women in Chromatography.”
Kinjal Bhatt and Ina Varfaj call AI a chromatography equalizer only if training and access keep pace, framing the risk as implementation, not technology.
Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) reveal lasting brain cholesterol loss after myelin damage.
Kinjal Bhatt would expose early-career scientists to the field sooner, while Ina Varfaj says a broken chromatography column taught her failure is normal.