High-Speed Countercurrent Chromatography Separation of Compounds from Herb
Researchers from the Chinese Academy of Sciences (Guangdong, China) used high-speed countercurrent chromatography to purify two benzoxazinoid glucosides from Acanthus ilicifolius L.
Researchers from the Chinese Academy of Sciences (Guangdong, China) used high-speed countercurrent chromatography to purify two benzoxazinoid glucosides from Acanthus ilicifolius L. The spiny herb is found in the mangroves of Southeast Asia and reportedly has medicinal properties. They first used n-butanol to extract the compounds from the plant. They then used a two-phase solvent system consisting of ethyl acetate, n-butanol, and 0.5% ammonium hydroxide for the single-step countercurrent chromatography separation of the two compounds. They also developed a two-step second separation process to obtain the compounds with higher purity.
HPLC 2025 Preview: Functionalized Monoliths as Selective Sample Preparation Materials
May 16th 2025Analyzing trace compounds from complex samples often requires purification and pre-concentration, and online coupling of solid-phase extraction (SPE) with liquid chromatography (LC) helps minimize analysis time and solvent/sample use. Monoliths with large macropores are ideal for this coupling due to their low back pressure and versatility in various formats.
Thermodynamic Insights into Organic Solvent Extraction for Chemical Analysis of Medical Devices
April 16th 2025A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.
