How Much Is Enough?

Scientists from Politecnico di Milan in Milano, Italy created a new optimization approach for chromatographically purifying oligonucleotides.

For trace quantitative analysis, the splitless technique is most used as an inlet capable of performing both split and splitless injections. In this and upcoming installments, we take a closer look at splitless injection.

In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.

Here is some of the most popular content posted on LCGC International this week.